TBL #4 Prototype + Class

Question 1

3 class of drugs to treat gout ATTACK

Answer 1

1. NSAIDs
2. Glucocorticoids
3. Colchicine

Question 2

Class of drugs to PREVENT gout

Answer 2

allopurinol (Zyloprim)

Question 3

3 classes of drugs to treat/prevent Osteoporosis

Answer 3

1.Vitamin supplementation
Calcium, Vitamin D

2.Drugs that decrease bone resorption (osteoclast activity = bone breakdown)
Calcitionin-Salmon
Biphosphonates:alendronate (Fosamax) 
Estrogen replacement (Premarin)
SERMs
Denosumab (Prolia)

3.Drugs that increases bone formation
Parathyroid Hormone (Forteo)

Question 4

5 drugs that decrease bone resorption

Answer 4

1. Calcitionin-Salmon
2. Biphosphonates: alendronate (Fosamax)
3. Estrogen replacement (Premarin)
4. SERMs- raloxifene (Evista)
5. Denosumab (Prolia)

Question 5

class of drugs that increases bone formation

Answer 5

teriparatide (Forteo)

Question 6

3 broad classes of drugs for RA

Answer 6

1. NSAID
2. Glucocorticoids
3. DMARDs
   - Non Biologic: Methotrexate (Rheumatrex)
   - Biologic DMARDs: Tumor Necrosis Factor Antagonists- 
Prototype: etanercept

Question 7

Colchicine

Answer 7

Acute gout

Question 8

allopurinol (Zyloprim)

Answer 8

prevent gout

Question 9

calcium, dose?

Answer 9

prevent/ treat OP

1200

Question 10

vitamin D, dose?

Answer 10

prevent/treat OP

800-1000

Question 11

calcitonin-salmon

Answer 11

prevent bone resorption (aka Xclast), OP

Question 12

alendronate (Fosamax)

Answer 12

Biphosphonates

prevent bone resorption (aka Xclast), OP

Question 13

conjugated equine estrogens (Premarin)

Answer 13

Estrogen Replacement

prevent bone resorption (aka Xclast), OP

Question 14

raloxifene (Evista)

Answer 14

Selective estrogen-receptor modifiers (SERM)

prevent bone resorption (aka Xclast), OP

Question 15

Denosumab (Prolia)

Answer 15

Monoclonal Antibody

prevent bone resorption (aka Xclast), OP

Question 16

teriparatide (Forteo)

Answer 16

Increases Bone Formation (aka Pro blast), OP

Question 17

Methotrexate (Rheumatrex)

Answer 17

Non Biologic DMARDs-( Disease modifying antirheumatic drugs ), RA

Question 18

etanercept

Answer 18

Tumor Necrosis Factor Antagonists

Biologic DMARDs, RA