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Kol- Pharm 323 Spring > exam 3 > Flashcards

exam 3 Flashcards

1
Q

drugs we need to know about overdosing/toxicity

A

imipramine- suicide risk, messes up your<3
lithium - no antidote- .4-.8
phenytoin- 10-20 mcg
triazolam

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2
Q

schedule 5?

A

gabapentin, pregabalin

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3
Q

no grapefruit and rash report?

A

carbamezapine (epilpep)

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4
Q

epileptic drug that is hepatotoxic and blood dyscrasia?

A

valproic acid

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5
Q

purple glove and gums?

A

phenytoin

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6
Q

Temporary paresthesia and itching (groin)

A

fosphenytoin

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7
Q

drug increases its own metabolism?

A

carbamezepine

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8
Q

Serotonin Syndrome (SES) vs Serotonin Withdrawal Syndrome

A

—–Serotonin Withdrawal Syndrome

Dizziness, headache, nausea, sensory disturbances, tremor, anxiety, dysphoria
- Begins within days to weeks , Persists 1-3 weeks

—–Serotonin Syndrome (SES)
mental status changes, hypertension, tremors, fever and sweats, hyperpyrexia, or ataxia
-2-72 hours after treatment starts

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9
Q

these 2 block reuptake if serotonin and NE

A

imipramine (Tofranil)

venlafaxine (Effexor)

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10
Q

imiprinine does not play nice w/ which other class of antidepressant?

A

MAOI

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11
Q

drugs to give @ bedtime

A

-imipramine

late in day = donepezil

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12
Q

take in morning

A
  • alendronate
  • fluoxetine
  • selegiline
  • pramipexole
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13
Q

MAOI + other antidepressant or sympathomimetic=

A

hypertensive crisis

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14
Q

MAOI + antihypertensive=

A

hypotension

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15
Q

MAOI + antidiabetic drugs=

A

hypoglycemia

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16
Q

MAOI + meperidine (Demerol)=

A

hyperpyrexia

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17
Q

14 day window b/w taking antihypertensive, antidiabetic, meperidine, other antidepressants with _______

A

MAOI

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18
Q

MAOI + Tyramine foods =

A

hypertensive crisis

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19
Q

dosing for colchicine

A

1.2 mg loading then .6 mg I hr later. Max 1.8/24 hrs.

20
Q

no grapefruit and rhabdo?

A

colchicine

21
Q

this drug has only one regular side effect but cannot play with warfarin

A

allopurinol

22
Q

penia vs porosis scores

A

Osteopenia- low bone mass T-score -1 to -2.5

Osteoporosis- T score -2.5 or more

23
Q

calcium + ______ _______ containing foods = sad

A

oxalic acid

24
Q

dosing for Ca and Vit D

A

Ca = 1200 / 2

Vit D = 800-1000

25
Q

intranasal Osteoporosis drug?

A

calcitonin salmon

26
Q

OP drug w/ esophagitis risk

A

alendronate

27
Q

2 drugs w/ osteonecrosis of jaw risk

A

alendronate

denosumab

28
Q

OP drug w/ risk for DVT an PE

A

SERM - think blood SERuM

29
Q

RANKL goes w/ who

A

denosumab

RANK receptor stimulates formation of osteoclasts
-this drug prevents receptor activation and inhibits osteoclast formation- aka RANKL inhibitor

30
Q

SQ OP drugs

A

calictonin-salmon
denosumab
teripartide

Deno came to Teri’s party in Cali

31
Q

SQ- etanercept or methotrexate?

A

etanercept

32
Q

test for TB prior, watch for hep b activation=

A

etanercept, methotrexate

33
Q

use folic acid supplement to help your tummy w/ which drug

A

methotrexate

p.s. category x

34
Q

all benzo’s potentiate

A

GABA

35
Q

flumazenil (Romazicon) is antidote for ________. It is given how?

A

triazolam

over 15 seconds. Repeat Q min. Effects last 1 hour.

36
Q

3 drugs = no grapefruit =

A

colchicine
carbamezpine
buspirone

Don’t bring a Grapefruit in my Car or the Bus or the Colcheesey factory

37
Q

prolonged qt interval long term use?

A

hydroxyzine

38
Q

prototype for benzo anxiety?

A

diazepam

39
Q

triazolam effects what 3 systems

A

cns, cv, resp

40
Q

avoid high protein meal with?

A

levadopa

41
Q

anticholinergic effects with

A

amantadine
benztropine
imipramine

42
Q

bronchoconstriction w/ what alz drug?

A

donepezil (increase ACH)

43
Q

ACH and alz ? ACH and Parkinsons?

A 
ALZ = not enough ACH
Parkinson's = too much ACH
44
Q

nystagmus w/ what 2 antiep

A
  • phenytoin- toxicity

- gabapentin- regular side effect

45
Q

suppress your bone marrow

A

carbamezepine

methotrexate

46
Q

admin rate for phenytoin? only compatible w? what kind of fluids?

A

<50mg/ min = SLOW

NS

Kol- Pharm 323 Spring (41 decks)

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