Exam 4 Flashcards
cimetidine + metformin =
lactic acidosis
pioglitizone is not for which patient population
Heart Failure –> fluid retention
Non insulin DM drug that can cause liver dysfunction?
acarbose
2 non insulin DM that are Sub Q
exanatide and pralmintide
have to go under the tide (water) to give it (water is the skin)
DM drugs to give 30-60 minutes before meal
coming soon
DM drugs to give with the tray
aspart (rapid)
acarbose ( w/ first bite of food)
DM drug that has 1 week formulation
exanatide
which n/v drug has risk of prolonged qt interval?
ondansetron ….use caution in bradycardia, electrolyte abnormalities
which n/v drug to treat gastroenteritis
ondansetron
which antiemtic drug can’t mix w/ warfarin and oral contraceptive?
aprepitant
which anti emetic drug has sxs of asthenia (loss of strength/energy) ?
aprepitant
which n/v drug has an unknown MOA ?
dexamethasone
which n/v drug can cause retrograde amnesia ?
lorazepam
which n/v drug is used to treat toxins
metoclopramide (dopamine antagonist)
which n/v drug has risk of extravasation?
promethazine (phenothiazine – dopamine antagonist)
which n/v drug is used as anti-emetic + improve motility
promethazine
which n/v drug cannot be used in <2 year old b/c of risk of resp depression
promethazine
which n/v drug when used long term can cause irreversible tardive dyskinesia ?
promethazine
which n/v drug can also stimulate apetite?
dronabinol
which n/v drug can cause dysphoria and temporal disintegration?
dronabinol
which n/v drug is used to treat motion sickness?
hydroxyzine
where does hydroxyzine work?
muscarinic receptors in the inner ear
which drug for IBD inhibits prostaglandins?
sulfalazine (5 amino salicylate)
which GI drug do we need to check for sulfa allergy with?
sulfalazine
Do we give sulfalazine before or after meals?
after
Which IBD drug can cause joint pain (arthralgia)
sulfalazine
use of sulfonylurea’s (glipizide) with which drug will increase risk of hyopglycemia?
exantide (GLT incretin)
malaise, hyperventilation, somnolence are s/s of what when taking metformin?
lactic acidosis
give oral drugs 1 hour before which 2 non insulin dm meds are given?
exanatide and pramlintide
*note both of these are sq injections
what class of drugs is glipizide?
sulfonylurea = increase insulin prdxn from pancreas
which non insulin drug has cold symptoms
DPP4 inhibitor aka Sitagliptin
2 non insulin drugs w/ pancreatitis side effect?
sitagliptin, exanatide
can you mix pramlintide w/ insulin?
nope!
does pramlintide cause hypogylcemia?
if mixed with insulin - occurs 3 hours after
non insulin DM med w/ risk of amputation and urosepsis?
canagliflozin
cimetidine does not play nicely w/ which 2 non insulin DM drugs?
metformin (biguanide) and glipizide (sulfonylurea)
which drug for IBD inhibits tumor necrosis factor?
infliximab
which laxative needs to be taken with FOOD and water?
lubiprostone
which laxative is for treating IBS, chronic/idiopathic constipation, and opioid constipation?
lubiprostone
omeprazole vs cimetidine - how long to take?
cimetidine = 4-6 weeks omeprazole = 4-8 weeks
can cause hypoglycemia
- glipizide
- repaglinide
- acarbose (w/ insulin/sulfonylurea)
- exanatide (w/sulfonylurea)
- pramlintide (w/ insulin)
+ aspart and NPH have risk
non insulin DM that causes GI symptoms
- metformin
- pioglitizone
- exanatide
- pramlintide
non insulin DM drugs (2) that causes hypoglyceimia and weight gain
- glipizide
2. repaglinide
