Prototypes + class Flashcards
class of chemo drugs that target S phase of cell cycle
◦ Antimetabolites
Class of chemo drugs that target G2 phase of cell cycle?
taxanes/taxoids
Class of chemo drugs that target M phase of cell cycle?
◦ Vinca alkaloids
Chemo drugs that have killing action REGARDLESS of cell cycle phase?
◦ Alkylating agents
◦ Antitumor antibodies
4 types of cytotoxic agents
a) Alkylating Agents
b) Antimetabolites
c) Antitumor antibiotics
d) Mitotic Inhibitors
prototype for hormone/hormone antagonist chemotherapy
tamoxifen (Nolvadex) –> SERM
2 classes of targeted therapies for cancer (nommy little bits)
nibs and mabs
2 types of biological response modifiers?
- immunostimmulants: interlukin and interferons
2. immunosuppressant
2 types of immunostimulants
interleukins
interferons
Classes of drugs to treat PUD (5)
- Antibiotics for H.Pylori
- Anti Secretory
- Mucosal Protectant
- Prostaglandin Agent
- Antacid
3 types of anti secretory agents:
- H2Blockers
- Proton Pump Inhibitors
- Muscarinic antagonist ??? (she never really talked about these but listed it. lmk if I missed a beat on this)
prototype of H2 blockers
- Prototype: cimetidine (Tagamet) –> in the drug book, original H2 blocker
- Also Know: famotidine (Pepcid) –> more commonly used
prototype for anti secretory: proton pump inhibitor
omeprazole (Prilosec)
prototype for mucosal protectant
Sucralfate
Prostaglandin Agent prototype
misoprostol (Cytotec)
different kinds of antacid compounds (elements)
aluminum
magnesium
calcium
sodium
prototype for Serotonin Receptor Antagonists
ondansetron (Zofran)
prototype for Substance P Neurokinin1Antagonists
aprepitant (Emend)