PROTOTYPE + Class TBL 2, antidotes Flashcards

1
Q

atorvastatin (Lipitor)

A

HMG-CoA Reductase Inhibitors aka “Statins”

Lipid lowering

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2
Q

colesevelam (Welchol)

A

Bile-Acid Sequestrants

Lipid Lowering

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3
Q

Ezetimibe (Zetia)

A

Cholesterol Absorption Inhibitor

lipid lowering

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4
Q

gemfibrozil (Lopid)

A

Fibric Acid Derivatives (Fibrates)

lipid lowering

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5
Q

evolocumab (Repatha)

A

Monoclonal Antibodies “mabs”
-PCSK9 inhibitors

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6
Q

Heparin (unfractionated)

A

anticoagulant

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7
Q

protamine sulfate

A

antidote: Heparin + LMW hepartin

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8
Q

enoxaparin(Lovenox)

A

Low Molecular Weight Heparin

anticoagulant

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9
Q

Warfarin (Coumadin)

A

Vitamin K antagonist

anticoagulant

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10
Q

Warfarin antidote

A

Vitamin K

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11
Q

dabigatran (Pradaxa)

A

Direct Thrombin Inhibitors

Anticoagulant

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12
Q

idarucizumab (Praxbind)

A

dabigatran (Pradaxa) antidote

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13
Q

apixaban (Eliquis)

A

Direct Factor Xa Inhibitors

-anticoagulant

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14
Q

Rivaroxaban (Xarelto)

A

Direct Factor Xa Inhibitors

anticoagulant

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15
Q

andexanet alfa (AndexXa)

A

antidote for
Direct Factor Xa Inhibitors
Rivaroxaban (Xarelto)
apixaban (Eliquis)

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16
Q

aspirin

A

antiplatelet

17
Q

clopidogrel (Plavix)

A

Adenosine Diphosphate Receptor (ADP) Antagonists

antiplatelet

18
Q

vorapaxar (Zontivity

A

PAR-1 Antagonists

antiplatelet

19
Q

abciximab (ReoPro)

A

Glycoprotein Ilb/llla Receptor Antagonists

antiplatelet

20
Q

alteplase (tPa)

A

Thrombolytics

21
Q

Lipid lowering prototypes

A
atorvastatin (Lipitor)
colesevelam (Welchol)
ezetimibe (Zetia)
ezetimibe + simvistatin (Vytorin)
gemfibrozil (Lopid)
evolocumab (Repatha)
Other: fish oil, cholestin
22
Q

Anticoagulant Prototypes

A
heparin
enoxaprin (Lovenox)
warfarin (Coumadin)
dabigatran (Pradaxa)
rivaroxaban (Xarelto) 
apixaban (Eliquis)
23
Q

Antiplatelet Prototypes

A

aspirin
clopidogrel (Plavix)
vorapaxar (Zontivity)
abciximab (ReoPro)

24
Q

Thrombolytics Prototypes

A

atleplase (tPa)