Surgical Tut - Colitis Flashcards

1
Q

colitis presents?

A

diarrhoea - typically bloody
abdo pain
fever

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2
Q

3 causes of infectious colitis? and their organisms

A

bacterial: C.diff, salmonella, shigella, camp, yersinia
viral: CMV
parasitic: entamoeba, cryptosporidium

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3
Q

who gets CMV colitis?

A

immunosuppressed,

transplant patients

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4
Q

history of someone with entamoeba hystolytica?

A

liver lesions
diarrhoea
recent travel

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5
Q

C.diff two types?

A

Toxin A - enterotoxin (osmotic diarrhoea)

Toxin B - cytotoxin (kills cells)

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6
Q

what Antibiotic likely to cause C.diff?

A

clindamycin
augmentin DF
cephs

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7
Q

C.Diff ask Abx therapy within what time frame?

A

6 weeks

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8
Q

C.Diff worse outcome for colon?

A

toxic megacolon: adynamic colon of more than 6 cm

subsequent perforation

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9
Q

how to treat C.Diff?

A

metronidozole
vanco
surg for colectomy

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10
Q

how many C.Diff produce toxin A vs. B

A

98% produce toxin A

100% produce toxin B

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11
Q

ischaemic colitis risk factors?

A

age, HTN, DM2,smoking

hypercoagulable
cocaine
extreme physical activity

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12
Q

right side colon/caecum susceptible to what ischaemia?

A

emboli from SMA

low flow states

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13
Q

sigmoid colon susceptible to ischaemia why?

A

IMA from atherosclerosis or AAA repair

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14
Q

ischaemic colitis from hospital causes?

A

post AAA

post CABG

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15
Q

why Abx in ischaemic colitis?

A

prophylaxis for translocation along wall

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16
Q

how to rule out colitis infections?

A

faecal MCS

17
Q

erythema nodosum association?

18
Q

association of UC?

A

Primary sclerosing cholangitis

19
Q

surgery for crohn’s?

A

Nope, need more surg and higher risk of complications

Risks of enterocutaneous fistula

20
Q

crohn’s extra intestinal manifestations?

A

Ankyspon
uveitis
erythema nodosum

21
Q

UC presents with?

A

PROCTITIS

frequent bloody stools, tenesmus
fever, weight loss

22
Q

whatis backwash ileitis?

A

UC backwashes inflammatory mediators through iliocaecal valve causes local ilietis?

23
Q

PSC with UC is what?

A

stricturing of biliary tree

24
Q

UC plus PSC gives you risk of?

A

dysplasia and colon cancer

25
smoking in crohn's?
bad
26
smoking in UC?
protective
27
inflammation in crohn's?
transmural
28
crohn's histopath?
granulomas neutrophils crypt abscesses
29
crohn's see what on colonoscopy?
deep fissures ulcers skip lesions
30
UC involved what infiltrate?
lymphocitic mostly
31
UC affects which structures in colon?
mucosa and submucosa
32
ulcers in UC?
may not
33
colitis involves usually what?
mucosa rather than transmural
34
diverticulum is what?
serosa and muscosa without muscle blow out where there's a gap in the vasculature
35
why does diverticulum occur?
constipation and higher pressures
36
diverticulitis happens where?
left mostly | right sometimes in Asians