Pathology - CNS Flashcards
1
Q
risk for alzheimers’?
A
age
trisomy 21
2
Q
pathology of alzheimer’s?
A
NFTs
plaques
vascular amyloid
3
Q
what is amyloid?
A
insoluble protein, B-pleated sheet rather than A-helix, resists enzymatic digestion
4
Q
how to detect amyloid?
A
congo red to green birefringence UV light
thioflavin T stain
5
Q
how can you get a haemorrhagic stroke after MI?
A
haemorrhagic transformation after anticoagulation
6
Q
3 sites for emobli
A
carotids
ventricular thrombus
valves
7
Q
what is encephalomalacia?
A
brain tissue is necrotic and liquifies and can leave a gap
8
Q
herpes simplex encephalitis is what kind?
A
necrotizing encephalitis, need high dose antivirals
9
Q
complication of encephalitis/meningitis for kids?
A
epiliepsy
10
Q
dementiaa just memory?
A
Nope, reason, personality, social as well
