Pathology Skin & Tumour Cancer

Question 1

causes of skin cancer?

Answer 1

genetic
carcinogens
surface toxins
viruses
other infections
inflammation
UV/sun exposure

Question 2

solar keratosis looks how?

Answer 2

thick keratin

disorganization of cells

Question 3

squamous cell carcinoma in situ called what?

Answer 3

Bowen’s disease

Question 4

what virus causes skin tumours?

Answer 4

HPV

Question 5

BCC aggressive? metastatic?

Answer 5

Aggressive

Not metastatic usually

Question 6

which BCC is mroe aggressive?

Answer 6

morphoeic pattern

Question 7

who is at more risk for metastatic SCC?

Answer 7

immunosuppressed

Question 8

where is SCC worse prognosis?

Answer 8

ear

lips

Question 9

where does SCC spread to?

Answer 9

regional nodes

Question 10

what is a keratoacanthoma? growth? looks how?

Answer 10

grows rapidly (6 weeks)
crater filled with keratin
symmetrical
can spontaneously regress

Question 11

why keratoacanthoma important to know?

Answer 11

SCC can mimic it

Question 12

freckles vs. moles

Answer 12

freckles are not raised

Question 13

how many mitoses are bad in melanoma?

Answer 13

> 1

Question 14

what skin lesions are pigmented and can bleed if caught on something?

Answer 14

not melanoma

probably seborrhoeic keratosis

Question 15

what best biopsy for a small/medium lesion?

Answer 15

excision

Question 16

something that’s raised and pigmented, doesn’t invade and above the epidermis is what?

Answer 16

seborrhoeic keratosis

Question 17

how to tell if haemangioma clinically?

Answer 17

try to blanch it because it is vascular

Question 18

multiple naevi called?

Answer 18

familial dysplastic naevus syndrome

Question 19

which melanomas bleed?

Answer 19

advanced stages if reaches blood vessels