Substance Abuse/ Dependance Flashcards
What is substance abuse vs dependence
abuse- ongoing misurse of a substance
dependence- chronic misuse of a substance accompanied by tolerance and withdrawal
This distinction is only found in ICD
Effects of alcohol on NTs (3)
- increased GABA activity
- Increased dopamine levels
- decreases effects of glutamate
What constitutes binge drinking
5+ drinks on one occassion
3 primary characteristics of FAS
1) retarted growth
2) Developmental delays and cognitive impairments
3) Atypical facial fx
what is delirium tremens
Intense syndrome caused by alcohol withdrawal during which a person becomes delirious, experiences intense tremors and terrifying hallucinations
What are 2 major consequences of chronic alcohol abuse
Cirrosis
Korsakoff syndrome= memory deterioration du to chronic alcohol abuse
3 major sedative hypnotics
- Barbituates
- Benzos
- Major tranquilizers
Types of stimulants (4)
Cocaine
Amphetamines
Nicotine
Caffeine
What are the natural opioids (3)
Naturally derived opiods can be broken down into alkaloid components to make
- Morphine
- Codeine
- Thebaine
What are the semisynthetic opiods
Heroin
Oxycodone
How does canabis produce its affects (NTs)
increasing GABA, glutamante, and dopamine
What is poly drug use
Refers to taking more than one drug at the same time OR people who are transitioning from one to another over time
What is the dopamine hypothesis of addiction
All versions of the dopamine hypothesis of addiction maintain that addictive drugs increase dopamine lvls in the brain
What is the reward deficiency syndrome of addiction
hypothesizes that addicted ppl take drugs to compensate for too little dopamine
-these types of ppl take drugs to increase dopamine because everyday activities don’t increase levels sufficiently
What is the incentive sensitization theory of addiction
Proposes that drugs cause people to seek them out by increasing dopamine sensitivity
(increased dopamine sensitivity results in increased alertness and on lookout for drugs)