Structure and Function of Skin 4

Question 1

Functions of the skin?

Answer 1

Thermoregulation
Waterproof barrier
Metabolism/Detoxification
Immune defence
Communication
Sensory function

Question 2

Main cause of toxic epidermal necrosis

Answer 2

drugs

Question 3

What happens in toxic epidermal necrosis (TEN)?

Answer 3

sweat alot more, shedding epidermis off of dermis

Question 4

What is erythroderma?

Answer 4

erythema affecting more than 90% of the skin causing widespread shedding

Question 5

What happens if the barrier function of the skin is lost?

Answer 5

dehydration from fluid loss,
hypoalbuminaemia from protein loss,
infection

Question 6

What happens if the thermoregulation function of the skin is lost

Answer 6

hypothermia

Question 7

What happens if the metabolic function of the skin is lost?

Answer 7

Disordered thyroxine metabolism

Question 8

What happens if the communicative function of the skin is lost?

Answer 8

Inability to display healthy skin

Question 9

Name some metabolic functions of the skin

Answer 9

thyroxine metabolism, vitamin d metabolism

Question 10

Name the beneficial effects of Vitamin D

Answer 10

increased calcium absorption, promotes mineralisation of bone

Question 11

How does the skin maintain temperature?

Answer 11

warm/cold-sensitive thermoreceptors

Question 12

What is eczema herpeticum?

Answer 12

disseminated herpes simplex virus that can affect the whole body

Question 13

Where are Pacinian Corpuscles typically located?

Answer 13

deep in the dermis surrounding a nerve fibre

Question 14

Where are Meissner corpuscles typically located?

Answer 14

in the dermis near the epidermis; have 1 nerve fibre around them

Question 15

Where are Merkel receptors located?

Answer 15

near the DE junction