Structure and Function of Skin 1

Question 1

What tissue is the epidermis composed of?

Answer 1

stratified squamous epithelium

Question 2

What tissue is the dermis composed of ?

Answer 2

connective tissue

Question 3

What embryological layer makes the epidermis?

Answer 3

Ectoderm

Question 4

What embryological layer makes the dermis?

Answer 4

Mesoderm

Question 5

Name the 4 layers of the epidermis

Answer 5

keratin layer, granular layer, prickle cell layer, basal layer

Question 6

What are Blaschko’s lines and how are they significant?

Answer 6

Developmental growth pattern of skin; if you see a linear problem with the skin it could be something congenital

Question 7

What are the main skin appendages?

Answer 7

Hair, nails, mucosae, glands

Question 8

What are the main movements of keratinocytes during their life?

Answer 8

Move from basal layer to keratin layer where they shed once dead

Question 9

How are the sole of the foot and palms of the hands different to the rest of the body in terms of structure?

Answer 9

Have no hair follicles but a lot more sweat glands and keratin

Question 10

How is skin growth psoriasis different from normal?

Answer 10

Cells grow too fast. Usually takes cells 28 days to move to top layer but in psoriasis it’s 4.

Question 11

Describe the components of the basal layer

Answer 11

Mainly stem cells and intermediate filaments eg keratin

Question 12

Main components of the granular layer?

Answer 12

Granules containing filaggrin and involucrin proteins; lamellar bodies, lots of lipids (acts as a seal), no nuclei

Question 13

Main components of keratin layer?

Answer 13

Corneocytes, keratin, filaggrin, lamellar granules