Structure and Function of Skin 3 Flashcards
Main role of dermo-epidermal junction
Differentiation of basal cells occurs here; is semi-permeable so acts as a filter
Layers of the dermo-epidermal junction?
Basal cells, lamina lucida, lamina densa, sub-lamina densa
What happens in bullous pemphygoid?
Antibodies attack proteins in the DE junction; triggered by vascular issues
What would show up on an immunofluorescence of someone with bullous pemphygoid
Get antibodies (mainly IgG) showing up
What do fibroblasts do and where are they found?
Collagen
Dermis
What is an angioma?
Area where blood vessels have dilated and enlarged
Main components of the dermis
fibroblasts, macrophages, mast cells, lymphocytes, langerhans cells, collagen, elastin, blood vessels, lymphatics, muscles
Name 2 somatic sensory nerve receptors and what they control
Pacinian corpuscle (vibration) and Meissners corpuscles (touch)
Are sweat glands autonomic or sensory
autonomic
What is neurofibromatosis
Overgrowth of nerve endings
Which parts of a hair follicle are epidermal and dermal
epidermal- top
dermal- papilla
Name the different types of skin gland
Sebaceous
Apocrine
Endocrine
Functions of sebaceous glands
control moisture loss
protection from fungal infection
Where are sebaceous glands most commonly found?
face and chest
Where are the apocrine sweat glands most commonly found?
axillae and perineum
