Dermatitis/Eczema Flashcards
what are the 2 phases in eczema?
acute phase
chronic phase
what does the acute phase of eczema present like?
papulovesicular erythematous lesions spongiosis ooze scaling/crusting
what does the chronic phase of eczema present like?
lichenification
elevated plaques
increased scaling
what causes lichen simplex dermatitis?
physical trauma by scratching
how does type 4 contact allergic dermatitis occur?
- antigen presented
- passed through and taken up by Langerhans cells
- Th cells primed to make memories for next contact
- on next contact, dermatitis triggered by migrated T cells to skin
Why would IgE testing not work in contact allergic dermatitis?
type 4 hypersensitivity so not involving IgE
features of contact irritant dermatitis that may present on the hand?
swelling erosion nail dystrophy lichenification fissures
other atopic diseases associated with eczema?
asthma, allergic rhinitis, food allergy
what would crusting on a rather inflamed eczema suggest?
staph aureus infection
eczema herpeticum morphology?
monomorphic punched out lesions
diagnostic criteria for atopic eczema?
3 or more of: visible flexural rash history of flexural rash history of atopy dry skin onset before age 2
eczema treatment?
- emollients
- avoidance of irritants
- topical steroids
- treat any infection
- phototherapy- UVB
- systemic immunosuppressants
- biological agents
what is the role of filaggrin in eczema?
protects skin barrier so if you have a mutation there you have a more unprotected skin barrier = atopic eczema
what does stasis eczema commonly follow?
increased hydrostatic pressure
oedema
red cell extravasation
