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Gastrointestinal > STI and GI Tract > Flashcards

STI and GI Tract Flashcards

1
Q

how are infections transmitted during sex

A 
trauma
IV drug user
fomties
ingestion 
sexual/genital secretions 
direct inoculation
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2
Q

risk factors for STIs

A 
<25 years old
change in sexual partner
non condom use
men who have sex with men (MSM)
Hx of STI
large urban areas
social deprivation 
black ethnicity
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3
Q

where do STIs affect in the GI tract

A

can effect everywhere

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4
Q

where does hepatitis A/B/C effect in GI tract

A

liver biliary tract

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5
Q

where does shigella affect the GI tract

A

small and large bowel

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6
Q

where does amoebiasis affect the GI tract

A

large bowel

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7
Q

where does giardia affect the GI tract

A

small bowel

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8
Q

transmission of gonorrhoea

A

direct contact mucosal surfaces with infected secretions;
anal sex
trans mucosal spread
fomite

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9
Q

symptoms of rectal gonorrhoea

A 
short incubation period
lower abdominal pain
diarrhoea
rectal bleeding
anal discharge (mucus)
tenesmus 
change in bowel habit 
may be asymptomatic
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10
Q

associated symptoms of rectal gonorrhoea

A

urethral/vaginal discharge

dysuria

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11
Q

tests for gonorrhoea

A

proctoscopy
PCR
gram stain rectal swab

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12
Q

pathology of gonorrhoea

A

inflamed mucosae

purulent exudate

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13
Q

complications of gonorrhoea

A

abscess formation

increased susceptibility/transmissibility of HIV

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14
Q

management of gonorrhoea

A

ceftriaxone
test of cure
public health interventions

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15
Q

how is chlamydia transmitted

A

direct contact mucosal surfaces with infected secretions;
anal sex
trans mucosal spread
fomite

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16
Q

symptoms of rectal chlamydia

A 
mostly asymptomatic 
milder than gonorrhoea 
anal discomfort/itch
anal discharge (mucus/blood)
low abdominal pain 
altered bowel habit
associated symptoms
17
Q

tests for chlamydia

A

proctoscopy
gram stain rectal swab
CT
PCR

18
Q

management for chlamydia

A

doxycycline
test of cure
public health interventions

19
Q

epidemiology of lymphogranuloma venereum

A 
MSM (+HIV)
associated with;
group sex
drug use
syphilis
hepatitis C
20
Q

primary clinical features of lymphogranuloma venereum

A

ulcer

21
Q

secondary clinical features of lymphogranuloma venereum

A

inguinal syndrome

ano-rectal syndorme

22
Q

tertiary clinical features of lymphogranuloma venereum

A

strictures
fistulae
geneital elephantiasis

23
Q

tests for lymphogranuloma venereum

A

full STI screen

fexi-sigmoidoscopy

24
Q

management for lymphogranuloma venereum

A

doxycycline

public health interventions

25
Q

pathology of Lymphogranuloma venereum

A

friable rectal mucosa
large ulcers
contact bleeding

26
Q

why is test of cure important

A

if treatment does not cure diagnosis e.g. piles

may be differential diagnosis e.g. Lymphogranuloma venereum

27
Q

primary clinical features of syphilis

A

solitary painless ulcer

28
Q

secondary clinical features of syphilis

A 
mucosal patches and ulcers
mouth, anogenital, rectal 
condylomata lata 
systemic inflammation (eye)
hepatitis 
proctoscopy-colitis
29
Q

symptoms of syphilis

A 
multi-systemic disease;
pain defaecation 
blood mixed in stools 
crampy abdominal pains 
rash 
lymphadenopathy
30
Q

tests for syphilis

A

colonoscopy

rectal biopsy

31
Q

management for syphilis

A

benzathene penicillin
public health interventions
follow-up serology

32
Q

how is herpes transmitted

A

ano-genital

oro-anal

33
Q

symptoms of herpes

A 
pain
ulcers
painful defaecation 
bleeding 
peri-anal mucosa (may extend into rectum)
viraemic symptoms (primary infection)
34
Q

how is human papilloma virus transmitted

A

ano-genital

oro-anal

35
Q

signs of HPV

A

anal warts - can extend to rectum

36
Q

complications of HPV

A

increasing prevalence of AIN and anal cancers in MSM and HIV+ people

37
Q

HIV and the GI tract

A

gut associated lymphoid tissue is the largest immune compartment - GI in constant state of physiological inflammation
depletion of intestinal GALT

38
Q

clinical presentation of GALT loss

A 
unknown 
HIV enteropathies 
opportunistic infeciton 
persistent immune activation - microbial translocation 
accelerated immunosenescence

Gastrointestinal (71 decks)

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