STDS Flashcards
STD general
15-24 year olds, can be asymptomatic, treat partners, use ABX for coinfection
neisseria gonorrhea E/M/S/D
E:human only, bind non ciliated epithelium, opa protein type IV pili
S: opa invades epithelium, can spread to distant tissue
D: opa is antiphagocytic
how does gonorrhea evade immune
IGA1 protege, antigenic variation, opa phase variation
gonorrhea clinical
pelvic inflam, VID, infert/ectopic
gonorrhea gram stain
gram + diplococci
gonorrhea treatment
cefriaxone injection with azithromycin (or doxy)
trachomatis is
chlamydia
chlamydia E/M/S
E: elementary body infects, obligate intracellular, non phagocyte
M: multiple in vacuole, become reticulate body
S: Rb back to EB, lysis
chlamydia clinical
pelvic inflam, autoimmune arthtitis
chlamydia treat
AB that target RB- azythro or doxy
what kind of tissue does NG colonize?
mucosal
how are both transmitted?
sex and maternal fetal
which affect mucosal membranes
both
intracellular?
CT
extracellular?
NG
which are chronic?
both