STDS Flashcards
STD general
15-24 year olds, can be asymptomatic, treat partners, use ABX for coinfection
neisseria gonorrhea E/M/S/D
E:human only, bind non ciliated epithelium, opa protein type IV pili
S: opa invades epithelium, can spread to distant tissue
D: opa is antiphagocytic
how does gonorrhea evade immune
IGA1 protege, antigenic variation, opa phase variation
gonorrhea clinical
pelvic inflam, VID, infert/ectopic
gonorrhea gram stain
gram + diplococci
gonorrhea treatment
cefriaxone injection with azithromycin (or doxy)
trachomatis is
chlamydia
chlamydia E/M/S
E: elementary body infects, obligate intracellular, non phagocyte
M: multiple in vacuole, become reticulate body
S: Rb back to EB, lysis
chlamydia clinical
pelvic inflam, autoimmune arthtitis
chlamydia treat
AB that target RB- azythro or doxy
what kind of tissue does NG colonize?
mucosal
how are both transmitted?
sex and maternal fetal
which affect mucosal membranes
both
intracellular?
CT
extracellular?
NG