Anti Malarials Flashcards

1
Q

classes (4)

A

quinolone, antifolates, artemisinins, antibiotics

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2
Q

quinolone drugs:

A

quinine, chloroquinine, mefloquine, primaquine, tafenoquine

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3
Q

antifolaxe drugs

A

atavaquine/proguanil

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4
Q

artemisinin drugs

A

artemisinin, artemether, artesunate

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5
Q

antibioitics

A

doxy, clindamycin

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6
Q

which have QT

A

mefloquine and quinine

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7
Q

quinine use

A

Pf/Pv (with antibiotic), QT/hearing loss

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8
Q

chloroquinine use

A

Pf resistant- treat PV, give with other quinolone. Rash/retinopathy

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9
Q

primaquine use

A

Pv/Po LATENT. G6PD!!

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10
Q

tafenoquine use

A

Pf/Pv proph, Pv Latent!! (G6PD/ mental illness

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11
Q

which are G6PD

A

primaquine/tafenoquine

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12
Q

atavoquone/proguanil use

A

Pf pro and treat. Some GI, don’t use in significant renal failure

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13
Q

Artemisinin use

A

must use in combo, well tolerated

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14
Q

Doxy

A

pro/treat (in combo)

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15
Q

clindamycin

A

treat (in combo)

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16
Q

uncomplicated Pf treatment options

A

Artemether/lumafantrine, Malarone, quinine+ abs, mefloquine

17
Q

severe Pf treatment

A

arsenate IV, followed by uncomplicated option

18
Q

Pv/Po treatment

A

chloroquinine, then primaquine or tafenoquine (ONLY IF g6pd ok)