Anti Malarials Flashcards
classes (4)
quinolone, antifolates, artemisinins, antibiotics
quinolone drugs:
quinine, chloroquinine, mefloquine, primaquine, tafenoquine
antifolaxe drugs
atavaquine/proguanil
artemisinin drugs
artemisinin, artemether, artesunate
antibioitics
doxy, clindamycin
which have QT
mefloquine and quinine
quinine use
Pf/Pv (with antibiotic), QT/hearing loss
chloroquinine use
Pf resistant- treat PV, give with other quinolone. Rash/retinopathy
primaquine use
Pv/Po LATENT. G6PD!!
tafenoquine use
Pf/Pv proph, Pv Latent!! (G6PD/ mental illness
which are G6PD
primaquine/tafenoquine
atavoquone/proguanil use
Pf pro and treat. Some GI, don’t use in significant renal failure
Artemisinin use
must use in combo, well tolerated
Doxy
pro/treat (in combo)
clindamycin
treat (in combo)