Herpes Virus Flashcards
HSV transmission
close contact/fluids (NOT RESP)
which hsv does what
HSVI- cold sore, HSV2, genital
HSV: when do symptoms occur in course of infection?
usually reactivation
HSV clinical presentations
oral, genital, whitlow, occular
HSV entry
mucosal menbrane> epithelial cells. Primary infection usually asymptomatic
HSV spread
local PNS neuron endings to craniospinal gangion (TNG, sacral)
VSV spread
respiratory
VSV infections
chickenpox or shingles
VSV primary infection spread
travels to dorsal root ganglia
chickenpox symtpoms
centripetal rash, fever, lymphodema
VSV reactivation
shingles, epithelia cells of infected nerve
VSV vaccines
varicella, shingles, passive zoster immunoglobin
shingles clinical
unilateral painful rash, blisters
VSV treatment?
only shingles, acyclovir
shingles complications
post herpetic neuralgia and encephalitis
smallpox incubation period
2 weeks
EBV transmission
saliva
EBV clinical
adolescents- mono. fatigue, fever, strep symptoms
EBV spread
epithelial cells» beta lympocytes
latent EBV
in b lymphocytes, leads to cancer!! lymphomas and nasopharyngeal
diagnosed EBV
early: monospotpositive, later antibody
treatment EBV
support, protect spleen
CMV clinical
adults with mono, maybe more than once
CMV latent?
yes but really only reactivates in immunosuppressed
CMV diag
monospot negative
CMV complications
congenital hearing loss/brain issues (in primary infection)
