Beta Lactams: Cephalosporins

Question 1

cephalosporins general

Answer 1

bactericidal, resist beta lactamases, less allergies

Question 2

which cephalosporins work against enterococci?

Answer 2

NONE

Question 3

first generation drugs

Answer 3

cefazolin/ cephalexin

Question 4

first gen bugs

Answer 4

gram +: MSSA Gram - (E/K/P)

“oxacillin twin”

Question 5

first get clinical uses

Answer 5

MSSA bacteremia, skin/soft tissue

Question 6

second gen drugs

Answer 6

cefuroxime and cefoxitin

Question 7

cefuroxime bugs

Answer 7

Gram +, hflu with betalactamase, gram -: E,K,P

Question 8

Cefoxitin bugs

Answer 8

less gram -, bacterodis fragilis

Question 9

cefuroxime clinical

Answer 9

above diaphragm

Question 10

cefoxitin clinical

Answer 10

below diaphragm

Question 11

Third gen drugs

Answer 11

Ceftrioxone, Ceftazimide

Question 12

Ceftrioxone bugs

Answer 12

strep, gram -, some anaerobes

Question 13

Ceftrioxone clinical

Answer 13

community pneumonia meningitis

Question 14

Ceftrioxone adverse

Answer 14

biliary obstruction

Question 15

Ceftazimide bugs

Answer 15

ONLY GRAM NEG- PSEUDOMONAS

Question 16

Ceftazimide clinical

Answer 16

nonsocomial CNS/meningitis

Question 17

fourth gen drug

Answer 17

cefepime

Question 18

ceftaroline resistance

Answer 18

bind PB2a

Question 19

cefepime drugs

Answer 19

Broad +/-, no anaerobic, PSEUDOMONAS

Question 20

cefepime clinical

Answer 20

nosocomial infections

Question 21

cefepime adverse

Answer 21

renal neurotoxin

Question 22

fifth gen drug

Answer 22

ceftaroline

Question 23

ceftaroline bus

Answer 23

gram +, MRSA!!, oral anaerobes

Question 24

ceftaroline adverse

Answer 24

hemolytic anemia

Question 25

which cephalosporins work on MRSA?

Answer 25

CEFTAROLINE

Question 26

which cephalosporins work on pseudomonas?

Answer 26

Cefepime/ceftaroline (4/5th gen)