encephalitis and HIV

Question 1

definition

Answer 1

inflammation of brain parenchyma

Question 2

general symptoms

Answer 2

flu like, fever, mental status changes

Question 3

entry routes

Answer 3

CNS- olfactory nerve, peripheral nerve, hematogenous (most infections)

Question 4

can you treat encephalitis?

Answer 4

ONLY HERPES

Question 5

herpes encephalitis mechanism

Answer 5

PNS>CNS, often temporal lobe, usually reactivation!!

Question 6

herpes encephalitis damage

Answer 6

nerve apoptosis

Question 7

herpes encephalitis diag/treat

Answer 7

EEG/MRI/CSF… treat EARLY with asyclovir

Question 8

EEE clinical

Answer 8

systemic or encephalitis. energy hematogenous

Question 9

most common vector encephalitis in USA>

Answer 9

WNV!

Question 10

rabies symptoms

Answer 10

encephalitis, agation, salvation, hydrophobia, ascending paralysis

Question 11

rabies spread

Answer 11

8.22 mm/day. PNS> spinal cord> CNS> saliva

Question 12

diagnosed rabies with

Answer 12

PCR, CNS path> Negri bodies

Question 13

HIV acute symptoms

Answer 13

mono like, 2-6 weeks post exposure

Question 14

HIV entry

Answer 14

picked up by dendritic cells, brought to lymph tissue, infect CD4. Gp120 binds CD4 receptor and chemokine receptor CCr5 or CxCr4

Question 15

diagnosis

Answer 15

Ab (20 days) An (15 days)