Staph Flashcards
subsets of staph
epidermis, saprophytic, aures
s. epidermis
normally on skin, issue when there is a foreign body.
spread: exopolysaccharide slime layer
s. saprophyticus
normally in the GI, often cause of UTI
S. Aures (general)
most pathogenic staph. usually stopped by normal pyogenic immune response. nosocomial> community
S. Aures encounter/clinical presentation
furuncle, carbuncle, impetigo, cellulitis. Toxigenic: scalded skin, TSS, food poisoning
S aures entry
external nares, often on hospital workers, IV injection users
S aures multiplication
extracellular
S aures spread
staphlokinase, lipase, DNAse
S aures virulence factors
surface: fimbrae/pili. secreted: coagulase. Both: protein A, catalase, pore forming toxin
S aures diagnosis
ID staph first, then color: golden brown (vs white), Coagulase positive
S aures treatment
drain, antibiotic (b lactase resistant beta lactam). MRSA> vancomycinc
general staph
gram + cocci in CLUSTERS. no vaccines.
protein A
in S. Aures, binds immunoglobulin FC, blocks complement
how does s. epidermis stick to stuff?
exopolysaccharide slime layer
treat epidermis with
vancomycin