Monobactams, carbapenems, and Non Beta Lactam cell wall

Question 1

monobactam structure

Answer 1

just beta lactam ring

Question 2

monobactam drug

Answer 2

aztreonam

Question 3

aztreonam spectrum/use

Answer 3

norm, gram negative. PSEUDOMONAS- ok if PCN allergy

Question 4

carbapenem, general

Answer 4

broadest beta lactam, resists beta lactamases, MO MRSA

Question 5

imipenem/cilastatian

Answer 5

PSEUDOMONAS, ESb1

Question 6

similar drug to imipenem

Answer 6

meropenem!

Question 7

Non beta lactam cell wall class

Answer 7

glycopeptides

Question 8

non beta lactam cell membrane class

Answer 8

lipopeptides

Question 9

glycopeptide drug

Answer 9

vancomycin

Question 10

vancomycin

Answer 10

blind D ala D ala, block PBP, gram +, MRSA, CDIFF

Question 11

vancomycin adverse affects

Answer 11

kidney extortion, redman syndrome (histamine not allergy)

Question 12

lipopeptide drug and mech

Answer 12

daptomycin bind cell membrane, insert lipid tail, form potassium channel, mess up ions

Question 13

daptomycin

Answer 13

gram +, MRSA, entero, staph, strep… no pneumonia! surfactant

Question 14

daptomycin adverse

Answer 14

skeletal muscle toxicity

Question 15

what drug works against extended spectrum beta lactamases?

Answer 15

carbapenem

Question 16

which drug requires renal monitoring?

Answer 16

vanco