Enteric Diarrhea Bacteria!! Flashcards
locations
small bowel, ileum, colon
location and diarrhea type
SB: watery, ileum: mix water and blood/pus, Colon: blood/pus
four SB bacteria
s. aures, b. ceres, v. cholera, enterotoxigenic E. coli.
SB infections usually mediated by what
toxin! treat with rehydration!
b ceres gram stain
positive
ECEC
pili adhere, multiply, two toxin types
four ileum bacteria
S. NTS, S. Typhi, enterocolitis, campylobacter
NTS
-in other animals, E: uncooked meat, M: small I epithelium (facultative intracellular), s: usually localized, but spreads in immune suppressed. D: submucosa, LPS- some blood/pus
Typhoid
humans only, P-P or F-O
M/s: spreads to liver, spleen, gallbladder
treat: abs (cipro, ceftriaxone)
which have vaccines?
typhoid, cholera
what is campylobacter similar to?
NTS!
what are the three colon bacteria?
shigella dysenteria, enterohemorrhagic e coli, C diff
Shigella dysenteria
E: p/p, f/o, acid resistant, invade M cells
M/S: actin based
Damage: shiga toxin
HUS!
HUS
hemolytic uremia syndrome: hemolytic anemia, thrombocytopenia, renal failure 1 wk after diarrheal phase
EHER
E: fecal beef
M/SL colon epithelium (actin)
Damage : phage releases shiga toxin
NO ANTIBIOTIC
what has fever but doesn’t invade tissue?
C DIF
what are low ID50
Typhoid, shigella
what are high ID50
cholera, ETEC, NTS, EHEC, campluobacter
type III secretion systems
NTS, type, camplyobacter, shigella, EHEC
what is special about shigella and PH?
acid resistant, survives stomach, so low ID50
if fever and blood in stool, give antibiotics if severe except for
EHEC
