Somatosensory systems Flashcards
What things are sensed by the somatosensory system?
pain touch proprioception itch visceral (nonpainful stimulus i.e bladder)
What are the 4 stages of sensation
transduction
transmission
perception
modulation
What are the classes of neurons that mediate modulation of somatic sensations?
dorsal root ganglion neurons
trigeminal sensory neurons
What are the types of neurons in the dorsal root ganglion
type A (beta or delta) type C
Describe type A beta dorsal root ganglionic neurons
large, myelinated
Describe type A delta dorsal root ganglionic neurons
small, unmyelinated
Describe type C dorsal root ganglionic neurons
have schwann cells that just bundle C cells together, not myelinating
What type of dorsal root ganglionic neuron is responsible for pain, temp, itch sensation
type C dorsal root ganglionic neuron
What is the difference between slowly adapting and fast adapting neurons?
Slow adapting neurons give information on intensity and duration of stimuli by mediating its firing rate (slow = weak stim. fast = strong stim.); fast adapting neurons only transmit when there is a change in strength of stimulus
What is the purpose of two pt discrimination
touch your lip with two fingers and touch your thigh with two fingers; it is easier to discriminate between the feeling of each finger on the lips than the thigh
What are the kinds of mechanoreceptors responsible for touch
Meissner corpuscle
Merkel cells
Pacinian Corpuscle
Ruffini endings
Phoebe mainly makes rice
What are the superficial mechanoreceptors responsible for touch
Meissner corpuscle
Merkel cells
What are the deep mechanoreceptors responsible for touch
pacinian corpuscle
ruffini endings
What are the rapidly adapting mechanoreptors
Meissner corpuscle
Pacinian corpuscle
What are the slowly adapting mechanoreceptors
Merkel cells
Ruffini endings
What are the means of proprioception
Joint receptors (sensory receptors in joint + in joint capsule which transduce tension) and muscle receptors (muscle spindles lie parallel to the muscle fibre transducing length + Golgi tendons transduce tension)
What neurons transduce hot stimuli
A delta axons neurons
What neurons transduce cold stimuli
C axons (unmyelinated)
What neurons transduce dangerous stimuli
nociceptors
What are the modalities of nociceptors
Thermal Mechanical (both A delta fibres) Polymodal (C fibres) Silent
What determines nociceptor diversity
transduction molecule expression on the surface
What type of nociceptor causes sensitivity in an area following injury
silent nociceptors
Describe how A beta fibres bring action potentials to the somatosensory cortex
A beta fibres enter the dorsal coloums/medial lemniscal system. Ascending ipsilaterally in the spinal cord and conveys mechanosensory information from the limbs and trunk to the cortex via VPL to the thalamus. Then the second order neuron in the medulla dessucates to the contralateral side and ascends to the thalamus where the third order neuron is located and goes to the somatosensory system.
Describe how nociceptors signal the brain
through contralateral anterolateral system.
What are the divisions of the somatic sensory cortex
S1 - primary
S2 - secondary
+ posterior parietal cortex
What are the cytoarchitectonic divisions of S1
Brodmanns areas 3a, 3b, 1 and 2