Biology of stress Flashcards

1
Q

What is stress

A

sympathetic nervous system and hypothalamic-pituitary-adrenal axis (HPA axis)

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2
Q

What does HPA stand for in HPA axis

A

hypothalamic-pituitary-adrenal axis

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3
Q

What are the main areas of the brain in the HPA axis

A
hypothalamus
pituitary glands
adrenal glands
amygdala 
hippocampus

HPA AH

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4
Q

Describe the amygdala

A

concerned with emotion, motivation and fear

receives info on events in the world, asses danger and emotional information is conveyed to other brain regions where defensive action is organised

there are 2 amygdalae

releases CRF = corticotropin releasing factor

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5
Q

Describe the hypothalamus

A

control of emotional reactions, drinking and feeding

emotional reactions in the hypothalamus stimulate hormonal secretions from the pituitary

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6
Q

Describe the hippocampus

A

organising memory storage - retrieving memories stored in the cortex, one on each side of the brain

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7
Q

Describe the pre-frontal cortex

A

planning + organisation of behaviour based upon use of working memory

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8
Q

Describe the adrenal glands

A

adrenal cortex on outside of the gland releases cortisol directly into blood stream

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9
Q

What is ACTH

A

ACTH = adrenocorticotropic hormone, released by the pituitary gland

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10
Q

What type of hormone are cortisol + corticosterone

A

glucocorticoids

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11
Q

How do cortisol and corticosterone work

A

bind to glucocorticoid receptors in the hypothalamus, hippocampus, prefrontal cortex, pituitary gland

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