Epigenetics Flashcards
1
Q
Where does methylation of histones occur
A
CG dinucleotides
2
Q
What enzymes methylate cytosine
A
DNA methyltransferases
3
Q
What affect does methylation of cytosine have?
A
Direct inhibition of transcription
4
Q
What is indirect methylation
A
Repressive (not expressed) chromatin produced by some factor activating MePC2 (which methylates cytosine)
5
Q
What is an imprinted gene
A
Only expressed on either a paternal/maternal chromosome