Somato & Neruo 2 Flashcards

1
Q

Dorsal root ganglion

A

Location of cell bodies (ncb) of first order sensory neurons
Support cells = satellite cells (sc)
Unmyelinated and myelinated axons (ma)

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2
Q

Spinal cord organization for sensory pathways

A

Dorsal column (funiculus)
2 divisions
Faciculus Gracilis - carries info abt caudal body & hindlimb
Faciculus cuneatus - carries info abt cranial body & forelimb

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3
Q

Grey matter organization

A

Rexed laminae 1-9
1 - pain & temp
2 - modulation
3 - touch
4 - touch
5 - pain
6 - position
7 - motor to viscera
8 - modulation
9 - motor to skeletal muscle

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4
Q

Dorsal Somatosensory pathways

A

Dorsal column system
Relays in for abt touch, position, vibration

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5
Q

First order neurons in dorsal SS pathway

A

Cell bodies in DORSAL root ganglion
Axon ascends in dorsal funiculus (dorsal columns
- hindlimb in Fas Gracilis (medial)
- forelimb in Fas cuneatus (lateral)
Synapses in nucleus Gracilis & cuneate nucleus in medulla

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6
Q

2nd order neuron Dorsal SS pathway

A

Cell body in brainstem nuclei
Axon crosses midline in medial lemniscus
Synapses in thalamus

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7
Q

3rd order neuron in dorsal SS pathway

A

Cell bodies in thalamus
Synapses in sensory cortex

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8
Q

Where 1st, 2nd, 3rd dorsal SS pathway synapse

A

1st - nucleus Gracilis & cuneate nucleus in medulla
2nd - thalamus
3rd - sensory cortex

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9
Q

Where orders cross in dorsal SS pathway

A

1st - axon ascends in dorsal funiculus
2nd - axon crosses at midline in medal lemniscus
3rd - cell bodies in thalamus

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10
Q

Lateral Spinothalamic tract

A

Relays information abt pain and temperature
Three neuron pathways

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11
Q

First neurons in lateral Spinothalamic tract

A

Cell body in dorsal root ganglion
Synapses in dorsal root of spinal cord

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12
Q

2nd neuron in lateral Spinothalamic tract

A

Cell body in dorsal horn of spinal cord
Axon crosses midline
Ascends in lateral funiculus
Synapses in thalamus

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13
Q

3rd neuron of lateral Spinothalamic tract

A

Cell body in thalamus
Synapses in sensory cortex

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14
Q

Where neurons synapse in lateral Spinothalamic tract

A

1st - dorsal horn of spinal cord
2nd - in thalamus
3rd - sensory cortex

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15
Q

Where axon crosses in lateral Spinothalamic tract

A

1st - cell body in dorsal root ganglion
2nd - crosses at midline
3rd - cell body in thalamus

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16
Q

Ventral Spinothalamic tract

A

Relays info abt light touch (non painful touch)
Three neuron pathways

17
Q

First neuron in ventral spinolthalamic tract

A

Cell body in dorsal root ganglion
Synapses in dorsal horn of spinal cord

18
Q

2nd neurons in ventral spinolthalamic tract

A

Cell body in dorsal horn of spinal cord
Axon crosses midline
Ascends in lateral funiculus
Synapses in thalamus

19
Q

3rd order neuron in ventral spinolthalamic tract

A

Cell body in thalamus
Synapses in sensory cortex

20
Q

Where neurons synapse in ventral spinolthalamic tract

A

1st - dorsal horn of spinal cord
2nd - in thalamus
3rd - sensory cortex

21
Q

Where axon crosses in ventral spinolthalamic tract

A

1st - cell body in dorsal root ganglion
2nd - axon crosses midline
3rd - in thalamus

22
Q

What tract handles touch, position, vibration

A

Dorsal somatosensory pathways

23
Q

What tract handles pain & temperature?

A

Lateral Spinothalamic tract

24
Q

What tracts handles light undiscriminated touch?

A

Ventral Spinothalamic tract

25
Q

Other synapses in the spinal cord

A

Axons in the first order sensory neuron branch
Also synapse in local Interneurons
Basis of spinal reflexes
Modulation of ascending signals

26
Q

Descending tracts

A

Motor
Lateral corticospinal tract (motor)
Ventral corticospinal tract (motor)

27
Q

Ascending tracts

A

Sensory
Dorsal columns - Fine touch, Proprioception, vibration
Lateral Spinothalamic tract - pain, temperature
Ventral Spinothalamic tract - light touch

28
Q

Spinoreticular tract

A

Pain modulation and response to pain

29
Q

Spinovestibular tract

A

Information about posture and balance

30
Q

Spinocerebellar tract

A

Unconscious proprioception

31
Q

Thalamus

A

Diencephalon
Relay station for input to cerebral cortex
- all sensory information except olfaction
Located rostral to midbrain
Two halves join in midline at the inter thalamus adhesion (3rd ventricle)

32
Q

Thalamic nuclei

A

Specialized for different sensory modalities
Also involved in motor system
Ventral nuclei = relay for somatosensory information

33
Q

Primary somatosensory cortex

A

Located caudal to primary motor cortex
Areas of cortex correspond to body parts on opposite side of the body
Head - lateral
Tail - medial
Limbs - rostral

34
Q

Somatotropic map

A

Areas with more sensory receptors have a larger area within the cortex

35
Q

Function of an itch

A

Receptors: pruriceptors
Axons: C and A gamma
TRP receptors respond to chemical stimuli
Information ascends to the brain in the lateral Spinothalamic tract