sodium and water balance Flashcards
what is the equation
Na= mol Na/ 1l H20
Does water follow sodium?
Yeahhh
What can a decrease in extracellular fluid lead to?
hypotension, decreased BP, increased pulse, decreased urine output
How is sodium controlled?
by mineralocorticoid activity
what is mineralocorticoid activity?
sodium retention in exchange for potassium/ hydrogen ions
What are some steroids with mineralocorticoid activity?
aldosterone, cortisol
what does too much mineralocorticoid activity mean?
sodium retention
what does too little mineralocorticoid activity mean
sodium loss (water loss)
what is water controlled by
ADH
what does ADH cause
water reabsorption, antidiuretic effect
what does increased ADH do to the urine?
concentrated
What does little ADH do to urine?
diluted
what is th relationship between concentration and osmolality
increased conc= increased osmolality
what can too little Na be result of?
too little NA (increased sodium loss- addisons/ gut/ kidneys/skin or too much H20- SIAD (decreased excretion)
what can too much Na be result of
too much Na-rare , too little H20- increased water loss- Diabetes insipidus, decreased water intake