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Endocrine > Differentiated thyroid cancer > Flashcards

Differentiated thyroid cancer Flashcards

1
Q

what is the most common and second common type of thyroid cancer

A

papillary then follicular

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2
Q

what is the most common and second common type of thyroid cancer

A

papillary then follicular

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3
Q

what are DTC driven by?

A

TSH

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4
Q

what do thyroid cancers secrete?

A

thyroglobulin

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5
Q

Is DTC common in children?

A

no

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6
Q

what happens in the rate of women over the age of 40?

A

the rate plateaus

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7
Q

what is the epidemiology of men in DTC?

A

age increases, risk increases

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8
Q

what strong association is linked with DTC?

A

radiation exposure

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9
Q

What is the association with diet, FH, malignancies, smoking

A

NONE

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10
Q

what is the most common presentation of DTC?

A

small palatable nodes, some present with pathological fractures (uncommon)

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11
Q

how does papillary DTC spread?

A

via lymphatics

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12
Q

what disorder is associated with papillary thyroid canceR?

A

hashimotos thyroiditis

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13
Q

what is the mortality rate at 10 years-

A
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14
Q

What causes incidence of follicular carcinoma to be higher in certain regions?

A

iodine deficinecy

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15
Q

How does follicular carcinoma spread?

A

haematogenous/ lymphatics

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16
Q

What is the main investigation for papillary/ follicular carcinoma?

A

USS with fine needle aspiration of lesion

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17
Q

if vocal cord palsy is suspected what test should be done prior to surgery?

A

laryngoscopy

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18
Q

what is the main stay treatment for DTC?

A

surgery- sub total thyroidectomy

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19
Q

what does AMES stand for?

A

Age, Metastases, Extent of primary tumour, Size of primary tumour

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20
Q

what are some low risk patients?

A

young, 20year survival is 99%

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21
Q

who are in the AMES high risk category

A

metastases, extra thyroidal disease with papillary cancer, capsular invasion with follicular carcinoma

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22
Q

when should a sub/ tool thyroidectomy take place?

A

in high risk patients

23
Q

what is a common side effect post op?

A

hypocalcaemia- low T2/3/4

24
Q

Do you want the TSH to be high before or after surgery?

A

Before

25
Q

When should you stop T3/4 before surgery?

A

T3- 2 weeks prior and T4- 4 weeks prior

26
Q

after total remnant ablation, what should the TSH level be?

A

Lowww

27
Q

when should thyroglobulin be measured>

A

before op

28
Q

in which disease is recurrence in cervical lymph nodes commmoner

A

papillary

29
Q

what are DTC driven by?

A

TSH

30
Q

what do thyroid cancers secrete?

A

thyroglobulin

31
Q

Is DTC common in children?

A

no

32
Q

what happens in the rate of women over the age of 40?

A

the rate plateaus

33
Q

what is the epidemiology of men in DTC?

A

age increases, risk increases

34
Q

what strong association is linked with DTC?

A

radiation exposure

35
Q

What is the association with diet, FH, malignancies, smoking

A

NONE

36
Q

what is the most common presentation of DTC?

A

small palatable nodes, some present with pathological fractures (uncommon)

37
Q

how does papillary DTC spread?

A

via lymphatics

38
Q

what disorder is associated with papillary thyroid canceR?

A

hashimotos thyroiditis

39
Q

what is the mortality rate at 10 years-

A
40
Q

What causes incidence of follicular carcinoma to be higher in certain regions?

A

iodine deficinecy

41
Q

How does follicular carcinoma spread?

A

haematogenous/ lymphatics

42
Q

What is the main investigation for papillary/ follicular carcinoma?

A

USS with fine needle aspiration of lesion

43
Q

if vocal cord palsy is suspected what test should be done prior to surgery?

A

laryngoscopy

44
Q

what is the main stay treatment for DTC?

A

surgery- sub total thyroidectomy

45
Q

what does AMES stand for?

A

Age, Metastases, Extent of primary tumour, Size of primary tumour

46
Q

what are some low risk patients?

A

young, 20year survival is 99%

47
Q

who are in the AMES high risk category

A

metastases, extra thyroidal disease with papillary cancer, capsular invasion with follicular carcinoma

48
Q

when should a sub/ tool thyroidectomy take place?

A

in high risk patients

49
Q

what is a common side effect post op?

A

hypocalcaemia- low T2/3/4

50
Q

Do you want the TSH to be high before or after surgery?

A

Before

51
Q

When should you stop T3/4 before surgery?

A

T3- 2 weeks prior and T4- 4 weeks prior

52
Q

after total remnant ablation, what should the TSH level be?

A

Lowww

53
Q

when should thyroglobulin be measured>

A

before op

54
Q

in which disease is recurrence in cervical lymph nodes commmoner

A

papillary

Endocrine (23 decks)

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