Smith 2 - Manifestations of Dz Flashcards
Most likely cause of epistaxis in cattle
CVCT - caudal vena cava thrombosis
CVCT
culminates in rupture of pulmonary artery aneurysm into a bronchus
tachypnea, lethargy, painful cough, melena, anemia –> red foamy d/c, severe resp distress
Toxic Causes of Epistaxis in Ruminants
mercury, arsenic, warfarin, diphacinone, furazolidone, trichloroethylene-extracted feed, oak/acorn, bracken fern, moldy sweet clover, phytogenous selenium, oxalate, stachybotryotoxicosis, mycotoxicosis
Toxic Causes of Epistaxis in Horses
arsenic, warfarin, dicoumarol, stachybotrys, plants, moldy sweet clover, PA, fiddle neck, tansy ragwort
Toxic Causes of Cough in Horses
crofton weed, a-naphthyl thiourea, pentachlorophenol, organophosphate, carbamate
Common Causes of Cough in Ruminants
mannheimia hemolytica / pasturella multocida shipping fever, enzootic calf pneumonia histophilus somni pneumonia lungworm chronic abscesses - arcanobacterium pyogenes IBR, BHV-1 BRSV parainfluenza virus 3 mycoplasma pneumonia necrotic laryngitis / calf diphtheria
Toxic Causes of Cough in Ruminants
organophosphate, carbamate, mercury, iodine, insect fogging, levamisole (O/C), nitrogen dioxide, hairy vetch, sneeze weed, aflatoxins (C)
Drugs that cause increased temp
penicillins, sulfonamides, erythromycin, antihistamines, procainamide, quinidine, amphotericin b
Toxins causing increased temp in the horse
cantharidin, selenium, arsenic, mercury, chlorinated hydrocarbons, dinitrophenol, propylene glycol, trichloroethylene extracted feed
Plant Toxins causing increased temp in the Horse
PA, algae, castor bean, water hemlock, jimsyn weed, mycotoxins
Toxins causing increased temp in Ruminants
Arsenic, selenium, mercury, zinc, oil, kerosine, chlorinated hydrocarbons, iodine, paraquat, dinitrophenol, propylene glycol, trichloroethylene extracted feed, halothane
Plant Toxins causing increased temp in Ruminants
fescue, ergot, PA, algae, brassica, bracken fern, castor bean, water hemlock, milkweed, buttercup, rhododendron, gossypol, jimsyn weed
Infectious causes of Fever in the Horse
URT virus, strangles, pneumonia, GI parasites, enteritis, salmonella, PHF, DPJ, Endotoxemia, septicemia, septic arthritis, osteomyelitis, tracheal. abscess, peritonitis, tetanus, cellulitis / tenosynovitis, occult abscess, tumors
Infectious causes of fever in Ruminants
mastitis, metritis, pneumonia, hardware, peritonitis, septic neonate, GI toxemia, enteritis, abscesses, endocarditis, listeria, tetanus, BVD, foot rot, otitis media or interna, clostridial infections, histophilus somni, mycoplasma, m. Bovis, verminous pneumonia
Neoplastic causes of fever
ALL: lymphosarsoma
Horses: metastatic melanoma, SCC, fibrosarcoma
Causes of hemoptysis in ruminants
CVCT, aspiration pneumonia, pharyngeal/retrop abscess or trauma, thoracic trauma, FB, pulmonary aspergilliosis
Cyanosis
Hb saturation <80%
PaO2 usually <40mmhg
must have adequate Hb concentration
Causes of increased capillary permeability
trauma, infection, Endotoxemia, hypersensitivity vasculitis
Causes of increased hydrostatic pressure
CHF, venous thrombosis, liver dz obstructing portal vein, lymphadenopathy, cranial mediastinal mass, limb immobilization
Causes of enlarged LNs in ruminants
Caseous lymphadenitis - corynebacterium pt
Lymphosarcoma - bovine leukosis virus
Abscess / cellulitis
Causes of melena in Ruminants
abomasal ulcer, intussusception
VS
- cattle, horses, rarely sheep
- vesicles -> large ulcers, tongue involved
- teats and feet too
Bluetongue
- sheep, rarely goats or cattle
- large oral ulcers, esp dental pad and tongue, + gen vasculitis
- coronitis, muscle degeneration, lameness, pulmonary edema, face and ear edema
Contagious Ecthyma (Orf)
- sheep, goats
- proliferative scabby lesion on lips, fleshy growth on gums
- can be on dams teats
Bovine papular stomatitis
- round, dark red, raised papule on muzzle and hard palate
- sometimes esophagus
Foot-and-mouth
- Cattle, sheep, goats
- vesicles -> large ulcers
- teats and coronary bands
BVD/MD
- ulcers on hard palate, erosive stomatitis
- skin lesions, corneal edema, enlarged LNs, pneumonia, esophageal lesions, diarrhea
MCF - malignant catarrhal fever
- cattle and bison
- erosive stomatitis with ulcers, gen vasculitis
- purulent nasal discharge, corneal edema, enlarged LNs, cracking skin, CNS signs, severe D+, high fever
Pestes des Petits ruminants (PPR)
- sheep and goats
- erosive stomatitis
- severe D+, purulent ocular and nasal d/c
Alimentary IBR
- calves
- gray pinpoint pustules on soft palate and nares
- MINIMAL oral lesions
- rhinotracheitis, conjunctivitis, pneumonia
Icterus in Ruminants - Liver
PA, aflatoxicosis, fatty liver / fat cow syndrome
Hemolytic Icterus in Ruminants
Lepto, anaplasmosis, bacillary hemoglobinuria, piroplasmosis, babesiosis
anaplas = RBCs in cattle but neutrophils in horses!
Lesion Location - Ataxia
spinocerebellar tracts, spinal cord, brainstem, vestibular, cerebellum
Lesion Location - conscious proprioceptive deficit
fasiculus gracilis and fasciculus cuneatus and connections, spinal cord, brainstem, forebrain
Lesion Location - knuckling
usually LMN, ventral horn gray matter, SC
can be UMN, SC, brainstem
Lesion Location - abduction or adduction
spinocerebellar tracts, SC, brainstem, cerebellum
Lesion Location - hypermetria
cerebellum, cerebellar peduncles, spinocerebellar tracts
Lesion Location - circling
forebrain, vestibular nuclei, cerebellum
Lesion Location - paraplegia
UMN T2-S2
LMN L3-S2
Lesion Location - hemiplegia
ipsilateral brainstem or SC, cranial to T3
Lesion Location - coma
ARAS, diffuse forebrain
Lesion Location - obtunded
ARAS, forebrain
Lesion Location - seizures
forebrain
Lesion Location - Head pressing, compulsive walking
forebrain
Lesion Location - hyper/hypophagia
hypothalamus
Lesion Location - stiff neck
meninges or C spine
Lesion Location - head tilt
vestibular nuclei and medulla, cerebellum
Lesion Location - head tremor
cerebellum, basalganglia
Lesion Location - blindness
cerebral cortex, internal capsule, optic tracts, optic chasm, optic nerve, eye
Lesion Location - mydriasis
oculomotor nerve, midbrain, optic nerve, eye
Lesion Location - miosis
vagosympathetic trunk, ciliary ganglia, tectum, brainstem, C spinal cord
Lesion Location - ptosis
facial n, vagosympathetic trunk, cranial cervical ganglion, midbrain, oculomotor nerve, C C,
Lesion Location - ventrolateral strabismus
cerebellum, vestibular nucleus, oculomotor nerve
Lesion Location - dorsomedial strabismus
trochlear nerve
Lesion Location - medial strabismus
abducent nerve
Lesion Location - horizontal nystagmus
Nerve VIII (peripheral)
Lesion Location - vertical nystagmus
vestibular nuclei, peripheral vestibular receptor, cerebellum, vestibulocochlear nerve
Lesion Location - jaw drop
trigeminal motor nucelus (pons), trigem
Lesion Location - flaccid tongue
hypoglossal nucleus (medulla), hypoglossal n, lingual m
Lesion Location - facial paralysis
facial nucleus (medulla), facial n. or muscles
Lesion Location - facial analgesia
sensory trigeminal n, pons, forebrain
Lesion Location - dry eye
cranial nerve VII
Neurologic signs of copper deficiency
demyelination, pathologic vertebral fractures
-ataxia, recumbency
Neurologic signs of Vit E deficiency
demyelination
-ataxia, recumbency
Neurologic signs of Vit A deficiency
encephalopathy, convulsions, blindness
Neurologic signs of Mg deficiency
grass tetany, transport tetany, milk tremors
-convulsions, tremors, ataxia
Neurologic signs of K deficiency
weakness, postpartum recumbency
Neurologic signs of Ca or P deficiency
milk fever, pathologic vertebral fractures, tetany
-weakness, ataxia, recumbency
Neurologic signs of Vit E / selenium deficiency
nutritional myodegeneration
-weakness, ataxia, recumbency, sudden death
UMNs
UMNs are nerve cells completely within the CNS, cell bodies in the brain and axons that terminate in the brain or SC
Signs of UMN diseases
normal to increased spinal reflexes, variable weakness, variable increased m tone or spasticity
Signs of LMN diseases
decreased spinal reflexes, ataxia, mod to severe weakness, flaccid muscle tone, rapid atrophy of denervated muscles
Signs of dysfunction - CN I
loss of smell
Signs of dysfunction - CN II
blindness
Signs of dysfunction - CN III
ventrolateral strabismus, ptosis, dilated non responsive pupil
Signs of dysfunction - CN IV
dorsomedial strabismus
Signs of dysfunction - CN V
dropped or deviated jaw, loss of sensation to head and face
Signs of dysfunction - CN VI
medial strabismus
Signs of dysfunction - CN VII
facial paralysis, loss of taste rostral 2/3 tongue, decreased tear and saliva production
Signs of dysfunction - CN VIII
deafness, vestibular signs
Signs of dysfunction - CN IX, X, XI
dysphagia, laryngeal paralysis
Signs of dysfunction - CN XII
tongue paralysis
Pain hypersensitivity
manifests as hyperalgesia (exaggerated responses to painful stimuli) and allodynia (pain resulting from normally innocuous stimuli