Small Intestine and colon Part 2 Flashcards

1
Q

What is Graft vs. Host Disease

A

Rare medical complication following the receipt of transplant tissues from a genetically different person

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2
Q

When does the graft vs. Host Disease occur

A

after allogenic hematopoietic stem cell transplants. it targets the antigens on the recipient’s epithelial cells by donor T cells

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3
Q

What tends to happen with intestinal graft vs. host disease

A

manifests as watery diarrhea

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4
Q

What causes rice water stools

A

V. Cholerae

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5
Q

What bacteria is spread throughout the reheating of rice

A

B. cereus

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6
Q

What organism comes into into play after antibiotic use

A

C. difficile

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7
Q

What organism cause problems from eating left over meat and poultry

A

C. Perfringen

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8
Q

What EHEC come from

A

Undercooked hamburger

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9
Q

What does ETEC cause

A

Travelers diarrhea

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10
Q

What comes with Salmonella species

A

typhoid fever

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11
Q

What causes S. aureus

A

Picnic foods

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12
Q

What does shellfish cause

A

V. parahaemolytic

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13
Q

How does Norovirus start

A

through an outbreak

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14
Q

Who does rotavirus affect

A

infants

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15
Q

Who does cryptosporidium affect

A

immunocompromised

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16
Q

What does E. histolytica cause

A

Amebic dysentery

17
Q

What does G. lambia cause

A

smelling stool

18
Q

What is Irritable bowel syndrome

A

Chronic and relapsing abdominal pain, bloating, and changes in bowel habits including diarrhea and constipation

Psychological stressors – domestic abuse, sexual abuse, stress, depression

F>M

19
Q

What are the manifestations of the IBS

A

Abdominal pain & bloating relieved by defecation,Stool with mucus, NO blood

Results from inappropriate mucosal immune activation

IBD encompasses two major entities- Crohn’s Disease and Ulcerative Colitis

20
Q

What is Crohns Disease

A

it is a inflammatory bowel disease that effects the gastrointestinal tract from the mouth to the anus.

21
Q

What is the presentation of Crohns Disease

A

30 and 60 years
location is in the gum to bum (Terminal ileum)
No rectal Bleeding
No diarrhea
The abdominal pain comes and goes
there is fever
there is in urgency
Mimics appendicitis
it can reoccur after surgery and you will see ulcers, cobblestoning and pseudo polyps in the endoscopy
it has Skip lessions and is ASCA + on a test

22
Q

What is the Ulcerative Colitis

A

it is inflammation and ulcers in the colon.

23
Q

What is the presentation of UC

A

30 and 50 years
in the rectum with bleeding and diarrhea
there is no abdominal pain, fever and palpable mass
There is urgency and on endoscopy there is continuous inflammation and pseuopolyps
You will see toxic megacolon, rupture and peritonitis and has a high risk for adenocarcinoma with ANCA + test.

24
Q

What are some of the extra intestinal Manifestation of CD and UC

A

Erythema Nodosum - macrophages

Pyoderma Ganernosum - nectroic tissue ulcers, usually on legs

Ankylosing spondylitis - Bamboo spine - restrictive movement moving forward

Uveitis - inflammation of urea; WBC’s in anterior chamber

25
Q

What is Diverticulum

A

Diverticulum: abnormal sac like protrusion fro the wall of a hollow organ.

26
Q

What is Diverticulosis

A

it is multiple diverticula

27
Q

What is diverticulitis

A

it is the inflammation of the one or more diverticula: increase intraluminal pressure and food partial deposit, Erosion of wall, inflammation and focal necrosis.

28
Q

What are the clinical manifestation of Diverticulum

A

Fever, left lower quadrant tenderness, nausea, vomiting and diarrhea and constipation

29
Q

What will the lab test show for diverticulum

A

It will show leukocytosis with left shift. ( increase in immature leukocytes)

30
Q

What should you do if a female is showing leukocytosis

A

make her take a pregnancy test

31
Q

What are the clues for diverticulum

A
Abscess 
Fistula 
perforation 
hypotension and shock 
extreme tenderness on palpation 
abdominal righty and guarding 
rebound tenderness
32
Q

What is the presentation of diverticulosis

A

Painless bleeding
left lower quadrant
no fever
treatment is with diet modification and increase fiber and water intake

33
Q

What is the presentation of diverticulitis

A

Painful bleeding
left lower quadrant
fever due to inflammation
treatment: diet modification, surgery, water intake and antibiotics