Small Intestine and colon Part 1 Flashcards

1
Q

What causes the obstruction os the small intestine

A

80% are Lesions hernias, intestinal adhesion, intussusception and volvulus

10 to 15% are tumors, infraction and other causes of strictures, Crohn Disease

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2
Q

What are the manifestations of Intestinal Obstruction

A

Abdominal Pain and discomfort and vomiting and constipations

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3
Q

What is the mechanism of Intestinal Obstruction

A

Normal flow of intestinal contents is disrupted - proximal dilation + distal decompression

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4
Q

What are the complication of Intestinal obstructions

A

Bowel ischemia due to bloody supply being strangulated, inflammation leads to venous congestion, edema and distortion or normal bowel absorptive function - increased intraluminal fluid. Transudative fluid loss ( hypovolemia into peritoneal cavity, electrolyte disturbance
Shock
Perforation

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5
Q

What is the presentation of Small bowel Obstruction

A
Nausea and vomiting early 
Abdominal pain that comes and goes 
distension occurs 
constipation occurs 
Bowel sounds increased 
in X-ray the is an increase in air  fluid levels
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6
Q

What is the presentation in Large Bowel Obstruction

A
Nausea and vomiting late 
Abdominal pain that comes and goes 
distension occurs 
constipation occurs
Bowel sounds increased 
in X-ray the is an increase in air  fluid levels
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7
Q

What is the prestantion of Pseudo-Obstruction

A
Nausea and vomiting occurs 
Abdominal pain is minimal 
distension occurs 
constipation occurs 
Bowel sounds decrease 
in X-ray the is an increase in air
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8
Q

What are the causes of small bowel obstruction

A
S - stricture 
H - hernia - 2nd cause 
A- adhesion - MCC
V -volvulus 
I - intussception
N - Neoplasm 3rd cause 
G - Gallstones
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9
Q

What are the causes of large bowel obstruction

A

Cancer
Diverticulitis
Volvulus

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10
Q

What is adhesions

A

Fibrous Band that forms between tissues Natural part the body’s healing process after surgery, similar to how a scar forms. Adhesion extend from within one tissue across to another, usually across a virtual space such as the peritoneal cavity. adhesion formation post surgery typically occurs when 2 injured surfaces are close to one another. this often cause inflammation and cause fibrin deposition onto the damage tissues.

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11
Q

What is a hernia

A

Defect in fascia - protrusion of bowel into sac. Males are more likely than females. Most common is the indirect (50%).

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12
Q

What is the Progression of the Hernia?

A

Entrapment, Incarceration, Strangulation ( Blood supply to the part of the bowel is blocked) and Infarction

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13
Q

What are the risk factors of hernia

A
Chronic Cough
Pregnancy 
Constipation 
Obesity
Ascites 
Straining 
Hernia repair 
Heavy lifting
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14
Q

What are the features of Hernia

A

Bulging with the patients coughs, sits ups and goes away when the patient is upon or when reduces
REMEMBER MD’s don’t lie

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15
Q

What is Volvulus? What is the most common area

A

Rotation of a segment of bowel about its mesenteric axis.

Sigmoid Colon due to the shape

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16
Q

What is intussusception

A

Part of bowel folds into another section of bowel ( telescoping) Mostly seen in the Kids: M>F

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17
Q

What are the complications of Intussusception

A

Obstruction, infarction and necrosis

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18
Q

What are the clues of intussusception

A

Sausage shaped Palpable mass

Rectal Bleeding

Kids Crises and draws knees up to chest

DONUT!!!!! or Target sign!!!

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19
Q

What is a major of Intussusception

A

There may be HSP or Henoch-Scholein Purpura. This is mainly in kids that follows an upper respiratory infection. there may be vasculitis, purport on buttock and legs, along with abdominal pain and Arthritis.

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20
Q

What is colonic Pseudo-Obstruction and what are the types

A

Symptoms similar to intestinal blockage but no physical signs of blockage.

Paralytic ileus and Ogilvie’s syndrome

21
Q

What is paralytic ileus?

A

Temporary paralysis of myeneteic plexus. tends to occur in postoperative surgeries and medications

22
Q

What is ogilivie syndrome

A

Acute pseudo obstruction. tends to happen in bedridden patients that have a serious extra intestinal illness like trauma, infection and cardiac

23
Q

What is ischemic bowel disease

A

is a medical condition in which injury of the small intestine occurs due to not enough blood happens in the splenic flexure or the watershed region

24
Q

What are the causes of ischemic bowel disease

A
Clots 
Atrial Fibrillations 
DVT 
Cardiac Vegetation 
Malignancy 
Low Perfusion/ Hemorrhage 
CHF
Shock 
Dehydration 
Vasoconstriction drugs
25
What are the signs of Ischemic Bowel Disease
Sudden severe left sided abdominal pain and bloody stools
26
What is Necrotizing Enterocolitis
blood vessels have not completely developed. leads to bowel necrosis. That happens in premature infants
27
What is the sign and symptoms Necrotizing Enterocolitis
Poor feeding Abdominal distension Bloody stools
28
What is angiodysplasia
Vascular malformation of the gut that is present in older patients. the MCL is the cecum and ascending colon. It is the 2nd MCC of lower GI bleeding.
29
What is the MCC of Angiodysplasia
DIVERTICULOSIS
30
What is the associated angiodysplasia
aortic stenosis. vWF gets damaged due to high stress at the aortic valve and it leads to bleeding
31
What are hemorrhoids
Dilated anal and perianal collateral vessels that connect the portal and naval venous system to relieve elevated venous pressure with the hemorrhoid plexus.
32
What risk factors hemorrhoids
Constipation and straining, pregnancy, portal hypertension, obesity and heavy lifts
33
What steatorrhea and what are the signs
``` it is frothy, foul smelling stool. signs : Bloating Cramps Diarrhea Flatulence weigh loss ```
34
What are the causes of Steatorrhea
CF Celiac disease Crohn disease
35
What is Meconium ileus
the inability to pass the first feces meconium. is a sign of cystic fibrosis
36
What is a differential diagnosis of meconium ileus
Hirschsprung disease
37
What is Hirschsprung disease
it is the failure of neural crest cells to migrate and pass the meconium
38
What is a good clue for Meconium ileus
CLUE: child comes in with a history of multiple respiratory infection - CF
39
What is celiac disease
Celiac sprue or gluten sensitive enteropathy. immune mediate enteropathy triggered by the ingestion of gluten-containgn cereals ( wheat, rye or barley) in genetical predisposed people.
40
What are the stats on Celiac disease
Caucasian associated with outer autoimmune disease HLD-DQ2 and 8 Females more than males
41
What is the pathogenesis of Celiac disease
Gluten digested by luminal & brush order enzymes into amino acid Gliadin Gliadin is De-aminated by tissue transglutaminase (tTG) It then interacts with HLA-DQ2 or HLA-DQ8 Cytokines and ***anti-tissue transglutaminase***, anti- gliadin & anti-endomysial antibodies produced CD8+ cells produce IL-15 that triggers intra-epithelial lymphocytes These lymphocytes become toxic and damage the epithelium
42
What are the manifestation of celiac disease
``` Bloating cramps diarrhea gas weigh loss fatigue Bone - osteoporosis CNS - depression Skin - dermatitis Herpriormis ```
43
What is a complication of celiac disease
Cancer - t-ccell lymphoma
44
What is whipple disease
infection that is caused by trophermy Whippelli
45
What is the pathogenesis of whipple disease
PAS-positive macrophages in lamina propria | Block lymphatics & reabsorption of chylomicrons
46
What are the manifestation of Whipple disease
``` Fever Steatorrhea Polyarthritis Lymphadenopathy Increase skin pigmentation ```
47
What is lactose deficiency
Lactase are located in the apical brush border membrane of the villous absorptive epithelial cells
48
What are the types lactose deficiency
Rare; Autosomal recessive Acquired Native Americans, African Americans, Chinese Clues to diagnosis – symptoms resolve after stopping milk & milk products