Small Animal Exotic Diseases Flashcards

1
Q

what causes ehrlichiosis/anaplasmosis

A

rickettsia ticks

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2
Q

what are the species of ehrlichiosis/anaplasmosis

A

E. canis = monocytic ehrlichiosis

A. phagocytophilia = granulocytic ehrlichiosis

A. platys = thrombocytic ehrlichiosis

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3
Q

what are the acute clinical signs

A

Non-specific signs

  • Pyrexia
  • Lymphadenopathy

Petechiation, epistaxis

Pale mucous membranes

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4
Q

what are the acute clinical signs acute granulocytic ehrlichiosis (anaplasmosis)

A

lameness

joint swelling

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5
Q

what are the chronic clinical signs of ehrlichiosis

A

pancytopenias

  • Non-regenerative anemia
  • Thrombocytopenia
  • Leucopenia

Hyperglobulinemia

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6
Q

how is ehrlichiosis diagnosed

A

Hematology

Direct observation

  • Buffy coat smears
  • Lymph node, hepatic, splenic aspirates

SNAP test

Serology

PCR

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7
Q

how is ehrlichiosis treated

A

tetracyclines

  • doxycyclines

Prednisolone

  • low doses for short periods
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8
Q

what causes babesiosis

A

b canis var vogeli

b canis var canis

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9
Q

what are the tick vectors of babesiosis

A

dermacentor reticularis

rhipicephalus sanguineus

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10
Q

what are the acute clinical signs of babesiosis

A

Acute disease of variable severity

Non-specific signs

  • Lethargy, anorexia, pyrexia

Hemolytic anemia

  • Pale mucous membranes
  • Jaundice, bilirubinuria
  • Hepatosplenomegaly

Shock, DIC, death

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11
Q

how is babesiosis diagnosed

A

Hematology

  • Regernative anemia

Blood smear examination

  • Peripheral vein sampling
  • Erythrocytes
    • Just below buffy coat

Coombs test positive

  • May auto agglutinate

Serology

PCR

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12
Q

how is babesiosis treated

A

blood transfusions

imidocarb

  • pain, hepatotoxic

Prednisolone

  • low doses for short periods

Treat Ehrlichia as well

  • even if not present on blood smear
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13
Q

what causes borreliosis

A

borrelia spp

borrelia burgdorferi sensu stricto = main cause of lyme disease

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14
Q

how is lyme disease spread

A

ixodes spp of ticks

mice and deer are main hosts

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15
Q

what are the main signs of lyme disease in dogs

A

fever of unknown origin

shifting lameness

lymphadenopathy

renal failure (rare)

general malaise

  • anorexia
  • mild weight loss
  • depression
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16
Q

how is lyme disease diagnosed

A

Exposure to infected ticks

  • Geography/local knowledge
  • History of travel to affected areas

Consider differentials

  • IMPA

Consider co-infections

  • Ehrlichia/anaplasmosis

Hematology

  • No specific findings

Culture/direct ID

  • Unreliable

Serology

  • Large # of false positives
  • Seroconversion common in endemic areas

Response to antibiotics (doxycycline)?