Sliding filament theory Flashcards
What is it
Muscles use ATP as an energy source to contract
Myosin
Thick protein filament having a tail and 2 head regions
Actin
Thin protein filament of globular subunits, twisted like a double strand of beads
Sarcomeres
-unit for striated muscle
-during contraction, sarcomeres shorten and actin and myosin fibres slide past each other
During contraction the…
I-band - narrows
Z-lines/disks-closer together
A-band- stays the same
H-zone-narrows
Stage 1 - myosin grabs actin
-myosin head attaches to a binding site on the actin filament
-forms a cross bridge
-requires ADP to reach towards the actin
Stage 2 - pull
- myosin heads bends pulling the actin filament along
-ADP and phosphate (Pi) are released
-binding sites are revealed
-the ‘power stroke’ can proceed
Stage 3 - let go
-the ATP molecules attaches to the myosin head
-this breaks the cross bridge
Stage 4- the ATP molecule attaches to the myosin head
-this breaks the cross bridge