Skin Therapeutics, Skin-Systemic Diseases, and UVRs

Question 1

1 FTU = __g

Answer 1

0.5

Question 2

Drug: acute eruptions that necessitate relatively rapid amelioration

Answer 2

Clobetasol Priopionate 0.05%

Question 3

Drug: Class 1 prototype

Answer 3

Clobetasol Priopionate 0.05%

Question 4

Drug: Class 4 prototype

Answer 4

Triamcinolone 0.1%

Question 5

Drug: Class 7 prototype

Answer 5

Hydrocortisone 2.5%

Question 6

Drug: effective against most moderate spongiotic dermatoses involving the trunk and extremities

Answer 6

Triamcinolone 0.1%

Question 7

Drug: efficacious for mild eczema in children and adults

Answer 7

Hydrocortisone 2.5%

Question 8

Drug: efficacious for treating dermatoses involving anatomic regions such as the face, intertriginous areas, or groin

Answer 8

Hydrocortisone 2.5%

Question 9

Drug: not recommended for facial, intertriginous, or groin lesions

Answer 9

Triamcinolone 0.1% and Clobetasol Priopionate 0.05%

Question 10

FTU adult male body

Answer 10

40

Question 11

FTU for face and neck

Answer 11

2.5

Question 12

FTU for foot

Answer 12

2

Question 13

FTU for hand (front and back)

Answer 13

1

Question 14

FTU for leg

Answer 14

6

Question 15

FTU for one arm

Answer 15

3

Question 16

FTU for trunk

Answer 16

3.5

Question 17

Immunosuppressive effects of UV damage (3)

Answer 17

Decrease in Langerhans cells, Inhibitory cytokines, Decreased T cell activation

Question 18

Koilonychia can be a sign of ______ deficiency.

Answer 18

iron

Question 19

Lichen planus is associated with _______ infection.

Answer 19

Hepatitis C

Question 20

Major skin defense against UVR

Answer 20

melanin

Question 21

Porphyria cutanea tarda is associated with ______ infection.

Answer 21

Hepatitis B and C

Question 22

Pyoderma gangrenosum is commonly associated with _____.

Answer 22

IBD

Question 23

Skin finding associated with: Diabetes mellitus (insulin intolerance), endocrinopathies, drug reactions (rare), cancer

Answer 23

Acanthosis Nigricans

Question 24

Skin finding associated with: endocarditis (3)

Answer 24

splinter hemorrhages in nails, Janeway lesions, Osler nodes

Question 25

Skin finding associated with: Marfan Syndrome

Answer 25

Decreased subcutaneous fat

Question 26

Skin finding associated with: Neurofibromatosis

Answer 26

Neurofibromas, café au lait spots

Question 27

Skin finding associated with: Parkinson Disease, head trauma, HIV

Answer 27

Seborrheic dermatitis

Question 28

Skin finding associated with: PHACES syndrome

Answer 28

large hemangioma of the face and neck

Question 29

Skin finding associated with: Pulmonary hypertension with possible pericarditis (3)

Answer 29

Thickened skin over hands and fingers, skin tightening around mouth, Raynaud syndrome

Question 30

Skin finding associated with: sarcoidosis (development of pulmonary fibrosis) (3)

Answer 30

Hyperpigmented plaques, erosive and ulcerated plaques, granulomatous reaction in tattoos

Question 31

Sun Protection Factor: Refers to ____ rating only

Answer 31

UVB

Question 32

Systemic disease associated with skin findings: fuzzy hair / Hypertrichosis languinosa acquisita

Answer 32

Lung cancer (also throat and oral)

Question 33

Systemic disease associated with skin findings: rapidly enlarging, easy to bleed papules and nodules, especially on the face

Answer 33

Renal Cancer

Question 34

Systemic disease associated with skin findings: rapidly enlarging, easy to bleed papules and nodules, especially on the scalp

Answer 34

Breast/Lung Cancer

Question 35

Systemic disease associated with skin findings: scaly eruption, mouth sores, arthralgia, malar rash

Answer 35

Systemic Lupus Erythematosus

Question 36

Systemic disease associated with skin findings: seborrheic keratosis of rapid emergence (Leser Trellat)

Answer 36

Skin cancer

Question 37

Systemic disease associated with skin findings: Shawl sign

Answer 37

Dermatomyositis

Question 38

Systemic disease associated with skin findings: Sister Mary Joseph Node/Nodule

Answer 38

GI cancers

Question 39

Systemic disease associated with skin findings: tripe palms (fuzzy hair on palms)

Answer 39

GI cancers

Question 40

Systemic disease associated with skin findings: wood grain pattern (erythema gyratum):

Answer 40

Lung cancer

Question 41

Systemic disease with skin findings: blistering lesions on dorsal hands with sun exposure, atrophic scars:

Answer 41

Porphyria cutanea tarda

Question 42

Systemic disease with skin findings: purple polygonal pruritic papules on wrists and lower legs, sores in mouth

Answer 42

lichen planus

Question 43

Systemic side effects of long term topical steroid use (3)

Answer 43

Adrenal suppression; Cushing's syndrome; Growth retardation in children

Question 44

UV damage induces _____.

Answer 44

Innate immunity, apoptosis

Question 45

UV type: photoaging, DNA damage

Answer 45

UVA

Question 46

UV type: Sunburn, eye problems, DNA damage

Answer 46

UVB

Question 47

UVA damage causes formation of _____

Answer 47

Hydroxyguanosine

Question 48

UVB damages causes formation of _____

Answer 48

Thymine dimers, Pyrimidine-6,4-pyrimidone

Question 49

Vehicles: avoid hands, face, and groin

Answer 49

Ointment

Question 50

Vehicles: Best hydration

Answer 50

Ointment

Question 51

Vehicles: good for all body sites

Answer 51

Cream

Question 52

Vehicles: good for hair-bearing areas

Answer 52

Foam

Question 53

Vehicles: highest acceptance

Answer 53

Cream, Lotion/Solution, Foam

Question 54

Vehicles: low irritation

Answer 54

Ointment, Cream

Question 55

Vehicles: Oil in water base

Answer 55

Cream

Question 56

Vehicles: Significant sensitization

Answer 56

Cream, Lotion/Solution, Gel

Question 57

Vehicles: strong potency

Answer 57

Ointment, Foam, Gel

Question 58

Vehicles: Water in oil base

Answer 58

Ointment

Question 59

Wavelength: UVA

Answer 59

320-400nm

Question 60

Wavelength: UVB

Answer 60

280-320nm

Question 61

Wavelength: UVC

Answer 61

100-280nm