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Disease and Defense > Skin Therapeutics, Skin-Systemic Diseases, and UVRs > Flashcards

Skin Therapeutics, Skin-Systemic Diseases, and UVRs Flashcards

1
Q

1 FTU = __g

A

0.5

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2
Q

Drug: acute eruptions that necessitate relatively rapid amelioration

A

Clobetasol Priopionate 0.05%

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3
Q

Drug: Class 1 prototype

A

Clobetasol Priopionate 0.05%

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4
Q

Drug: Class 4 prototype

A

Triamcinolone 0.1%

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5
Q

Drug: Class 7 prototype

A

Hydrocortisone 2.5%

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6
Q

Drug: effective against most moderate spongiotic dermatoses involving the trunk and extremities

A

Triamcinolone 0.1%

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7
Q

Drug: efficacious for mild eczema in children and adults

A

Hydrocortisone 2.5%

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8
Q

Drug: efficacious for treating dermatoses involving anatomic regions such as the face, intertriginous areas, or groin

A

Hydrocortisone 2.5%

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9
Q

Drug: not recommended for facial, intertriginous, or groin lesions

A

Triamcinolone 0.1% and Clobetasol Priopionate 0.05%

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10
Q

FTU adult male body

A

40

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11
Q

FTU for face and neck

A

2.5

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12
Q

FTU for foot

A

2

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13
Q

FTU for hand (front and back)

A

1

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14
Q

FTU for leg

A

6

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15
Q

FTU for one arm

A

3

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16
Q

FTU for trunk

A

3.5

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17
Q

Immunosuppressive effects of UV damage (3)

A

Decrease in Langerhans cells, Inhibitory cytokines, Decreased T cell activation

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18
Q

Koilonychia can be a sign of ______ deficiency.

A

iron

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19
Q

Lichen planus is associated with _______ infection.

A

Hepatitis C

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20
Q

Major skin defense against UVR

A

melanin

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21
Q

Porphyria cutanea tarda is associated with ______ infection.

A

Hepatitis B and C

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22
Q

Pyoderma gangrenosum is commonly associated with _____.

A

IBD

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23
Q

Skin finding associated with: Diabetes mellitus (insulin intolerance), endocrinopathies, drug reactions (rare), cancer

A

Acanthosis Nigricans

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24
Q

Skin finding associated with: endocarditis (3)

A

splinter hemorrhages in nails, Janeway lesions, Osler nodes

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25
Q

Skin finding associated with: Marfan Syndrome

A

Decreased subcutaneous fat

26
Q

Skin finding associated with: Neurofibromatosis

A

Neurofibromas, café au lait spots

27
Q

Skin finding associated with: Parkinson Disease, head trauma, HIV

A

Seborrheic dermatitis

28
Q

Skin finding associated with: PHACES syndrome

A

large hemangioma of the face and neck

29
Q

Skin finding associated with: Pulmonary hypertension with possible pericarditis (3)

A

Thickened skin over hands and fingers, skin tightening around mouth, Raynaud syndrome

30
Q

Skin finding associated with: sarcoidosis (development of pulmonary fibrosis) (3)

A

Hyperpigmented plaques, erosive and ulcerated plaques, granulomatous reaction in tattoos

31
Q

Sun Protection Factor: Refers to ____ rating only

A

UVB

32
Q

Systemic disease associated with skin findings: fuzzy hair / Hypertrichosis languinosa acquisita

A

Lung cancer (also throat and oral)

33
Q

Systemic disease associated with skin findings: rapidly enlarging, easy to bleed papules and nodules, especially on the face

A

Renal Cancer

34
Q

Systemic disease associated with skin findings: rapidly enlarging, easy to bleed papules and nodules, especially on the scalp

A

Breast/Lung Cancer

35
Q

Systemic disease associated with skin findings: scaly eruption, mouth sores, arthralgia, malar rash

A

Systemic Lupus Erythematosus

36
Q

Systemic disease associated with skin findings: seborrheic keratosis of rapid emergence (Leser Trellat)

A

Skin cancer

37
Q

Systemic disease associated with skin findings: Shawl sign

A

Dermatomyositis

38
Q

Systemic disease associated with skin findings: Sister Mary Joseph Node/Nodule

A

GI cancers

39
Q

Systemic disease associated with skin findings: tripe palms (fuzzy hair on palms)

A

GI cancers

40
Q

Systemic disease associated with skin findings: wood grain pattern (erythema gyratum):

A

Lung cancer

41
Q

Systemic disease with skin findings: blistering lesions on dorsal hands with sun exposure, atrophic scars:

A

Porphyria cutanea tarda

42
Q

Systemic disease with skin findings: purple polygonal pruritic papules on wrists and lower legs, sores in mouth

A

lichen planus

43
Q

Systemic side effects of long term topical steroid use (3)

A

Adrenal suppression; Cushing’s syndrome; Growth retardation in children

44
Q

UV damage induces _____.

A

Innate immunity, apoptosis

45
Q

UV type: photoaging, DNA damage

A

UVA

46
Q

UV type: Sunburn, eye problems, DNA damage

A

UVB

47
Q

UVA damage causes formation of _____

A

Hydroxyguanosine

48
Q

UVB damages causes formation of _____

A

Thymine dimers, Pyrimidine-6,4-pyrimidone

49
Q

Vehicles: avoid hands, face, and groin

A

Ointment

50
Q

Vehicles: Best hydration

A

Ointment

51
Q

Vehicles: good for all body sites

A

Cream

52
Q

Vehicles: good for hair-bearing areas

A

Foam

53
Q

Vehicles: highest acceptance

A

Cream, Lotion/Solution, Foam

54
Q

Vehicles: low irritation

A

Ointment, Cream

55
Q

Vehicles: Oil in water base

A

Cream

56
Q

Vehicles: Significant sensitization

A

Cream, Lotion/Solution, Gel

57
Q

Vehicles: strong potency

A

Ointment, Foam, Gel

58
Q

Vehicles: Water in oil base

A

Ointment

59
Q

Wavelength: UVA

A

320-400nm

60
Q

Wavelength: UVB

A

280-320nm

61
Q

Wavelength: UVC

A

100-280nm

Disease and Defense (16 decks)

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