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Disease and Defense > Neoplasms and Cancer > Flashcards

Neoplasms and Cancer Flashcards

1
Q

Aggressive lung tumors that metastasize widely, especially to the brain

A

Small cell carcinoma

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2
Q

Benign or malignant? Cytologic uniformity

A

Benign

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3
Q

Benign or malignant? general loss of boundary between tumor and adjacent tissue

A

Malignant

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4
Q

Benign or malignant? Invasive, metastasizes

A

Malignant

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5
Q

Benign or malignant? cause injury both by local tissue destruction and distant dissemination and tissue destruction

A

Malignant

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6
Q

Benign or malignant? circumscribed/encapsulated

A

Benign

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7
Q

Benign or malignant? High rate of cell turnover

A

Malignant

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8
Q

Benign or malignant? injury by compression interference of adjacent structures

A

Benign

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9
Q

Benign or malignant? Necrosis

A

Malignant

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10
Q

Benign or malignant? well differentiated

A

Benign

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11
Q

Bind to interior surface of microtubule, stabilize microtubule against de-polymerization

A

Taxanes

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12
Q

Bind to tubulin at ends, stabilizing them

A

Vinca Alkaloids

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13
Q

In ______ tissues, there is little or no capacity for proliferation

A

non-dividing

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14
Q

In ______ tissues, there is normally little or no turnover but there is capacity for proliferation if needed

A

quiescent

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15
Q

Lung carcinoma characterized by cells attempting to form primitive gland-like structures (stain positive for mucin)

A

Adenocarcinoma

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16
Q

Lung carcinoma characterized by metaplasia of pseudostratified ciliated columnar epithelium to squamous epithelium

A

Squamous cell carcinoma

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17
Q

Moderately well differentiated adenocarcinomas arising in mucosal layer of bowel

A

Colorectal carcinoma

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18
Q

Name the drug class: 5-Flurouracil

A

Anti-metabolite

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19
Q

Name the drug class: Anthracyclines

A

Topoisomerase Inhibitor

20
Q

Name the drug class: Aromatase Inhibitors

A

Hormonal Agents

21
Q

Name the drug class: Bicalutamide

A

Hormonal Agents

22
Q

Name the drug class: Carboplatin

A

Cisplatin Analogue

23
Q

Name the drug class: Etosopide

A

Topoisomerase Inhibitor

24
Q

Name the drug class: Flutamide

A

Hormonal Agents

25
Q

Name the drug class: GNHR Analgoues

A

Hormonal Agents

26
Q

Name the drug class: Herceptin

A

Antibody

27
Q

Name the drug class: Imatinib

A

Kinase Inhibitor

28
Q

Name the drug class: Methotrexate

A

Anti-metabolite

29
Q

Name the drug class: Nitrogen Mustard

A

Alkylating Agent

30
Q

Name the drug class: Oxaliplatin

A

Cisplatin Analogue

31
Q

Name the drug class: Rituximab

A

Antibody

32
Q

Name the drug class: Tamoxifen

A

Hormonal Agents

33
Q

Name the drug class: Taxanes

A

Anti-Microtubule Agent

34
Q

Name the drug class: Vinblastine

A

Anti-Microtubule Agent

35
Q

Name the drug class: Vincristine

A

Anti-Microtubule Agent

36
Q

Pyrimidine Analog that is metabolized by thymidine kinase and inhibits DNA synthesis

A

5-Fluorouracil

37
Q

Reversible, competitive inhibitor of DHFR, which is required for purine nucleotide synthesis

A

Methotrexate

38
Q

Tumor Stage: T1/T2, N0, M0

A

I

39
Q

Tumor Stage: T1/T2, N1, M0

A

IIIA

40
Q

Tumor Stage: T3, N0, M0

A

IIA

41
Q

Tumor Stage: T3/T4, N2, M0

A

IIIB

42
Q

Tumor Stage: T4, N0, M0

A

IIB

43
Q

Tumor Stage: Tany, N2, M0

A

IIIC

44
Q

Tumor Stage: Tany, Nany, M1

A

IV

45
Q

Types of lung carcinoma most linked to smoking

A

Small cell and squamous cell

46
Q

Undifferentiated high grade lung cancer where cells may not produce keratin or mucin

A

Large cell carcinoma

47
Q

What type of malignant tumor is characterized by having a pre-malignant lesion and an in-situ phase?

A

Carcinoma

Disease and Defense (16 decks)

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