skin 2.1 Flashcards

1
Q

Herpes simplex

cause

A

HSV
HSV 1- oral inf.
HSV 2- genital inf.

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2
Q

Herpes simplex

sx

A

Systemic sx- fever, HA

Prodrome such as burning/tingling then Vesicles break out in same location

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3
Q

herpes labialis

A

on mucus membranes

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4
Q

Herpes whitlow-

A

inf on fingers

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5
Q

Herpes herpeticum-

A

generalized with previous condition of atopic dermatitis

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6
Q

Herpes simplex

dx

A

Zantac smear or viral culture

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7
Q

Herpes simplex

trmt

A

Valacyclovir

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8
Q

Herpes ophthalmicus and lead to

A

blindness

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9
Q

Herpes zoster

?

A

Latent varicella zoster virus reactivates
DO NOT MISS bc it can lead to post herpetic neuralgia
medical emergency

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10
Q

Herpes zoster

pe

A

Vesicles on red base in unilateral dermatomal pattern
MC on face and trunk
Herpes ophthalmicus if lesion on tip of nose→ hutchinson sign

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11
Q

Herpes zoster

dx

A

Usually none

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12
Q

Herpes zoster

trmt

A

Antivirals- valacyclovir
Topical
Pain meds

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13
Q

Varicella cause

A

Varicella zoster virus

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14
Q

Varicella sx

A

Prodrome of fever, chills, HA, malaise, ST, dry cough

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15
Q

Varicella pe

A

Itchy vesicles on trunk first then moves to palms, soles, and mucous memb
Dew drops on rose petal

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16
Q

Varicella trmt

A

Antihistamine

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17
Q

Bullous impetigo

?

A

Intraepidermal bacterial infection

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18
Q

MC in preschool age

A

Bullous impetigo

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19
Q

Bullous impetigo

cause

A

S aureus

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20
Q

Bullous impetigo

pe

A

clear/cloudy bullae
Crust after it ruptures
Honey crusted lesion

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21
Q

Bullous impetigo

dx

A

Gram stain shows s aureus

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22
Q

Bullous impetigo

trmt

A

ATB mupirocin GOLD std

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23
Q

Pemphigus vulgaris

?

A

Autoimmune disease with blistering of skin and mucous membranes
Antibodies against desmoglein, connections in epidermal cells

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24
Q

Pemphigus vulgaris

pe

A

Flaccid/superficial bullae that are 1-10cm wide and rupture easily
+ Nikolsky’s sign- apply pressure laterally and bulla extends
Oral mucosa affected before trunk

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25
Pemphigus vulgaris | dx
+ Immunofluorescence | Punch biopsy
26
Pemphigus vulgaris | trmt
Systemic steroids Immunosuppressants Die if untreated
27
Bullous pemphigoid | ?
Autoimmune disorder with large blisters | Autoantibodies directed towards hemidesmosomes, attach epithelial cells to bsmt membranes
28
Bullous pemphigoid | pe
Bullae on groin and armpits | - Nikolsky’s sign- apply pressure laterally and bullae won't extend
29
Bullous pemphigoid | dx
+ Immunofluorescence
30
Bullous pemphigoid | trmt
Systemic steroids Immunosuppressants Good prognosis
31
Dermatitis herpetiformis | pe
VERY itchy vesicular disease with grouped papules, vesicles, and urticarial plaques on elbows, butt, lower back, and shoulders Easy chair distribution
32
Dermatitis herpetiformis | dx
+ blood test for IgA Ab
33
Porphyria cutaneous tarda | ?
Metabolic disorder in heme biosynthesis path
34
Porphyria cutaneous tarda | causes
Alcohol | Need uroporphyrinogen to be converted to coproporphyrinogen in heme pathway
35
Porphyria cutaneous tarda | pe
Blisters on dorsum of hand and sun exposed areas Uroporphyrin excretion in urine Facial hair, mottled facial pigment, milia
36
Porphyria cutaneous tarda | dx
``` Photosensitivity Urine is dark brown and red under wood’s light High Uroporphyrin in urine High LFT High serum iron ```
37
Porphyria cutaneous tarda | trmt
Phlebotomy
38
Scabies cause
epidermis is infested with sarcoptes scabiei var hominis | Common in ppl living in close quarters
39
Scabies PE
Inflammatory papules Generalized pruritus with worse itch of life Nocturnal Hand webspaces, elbows, axillae, feet, groin No head involvement in adults
40
Scabies dx
Burrow that is 2-5 mm with serpiginous thread like line
41
Scabies trmt
Permethrin cream on entire body then repeat in 1 wk | Ivermectin - anti parasite
42
Norwegian scabies/crusted scabies-
widespread with high mite load; no itching
43
Lice aka pediculosis capitis | cause
Pediculosis humanus var capitis
44
Lice aka pediculosis capitis | sx
Intense itch
45
Lice aka pediculosis capitis | dx
See nits on scalp
46
Lice aka pediculosis capitis | trmt
Nit combing | Malathion lotion
47
6 ps of lichen planus
6 p’s: pruritic, polygonal, planar, purple, papules, and plaques
48
Lichen planus | cause
Unknown | Maybe meds
49
Lichen planus | PE
Wickham’s striae- white lines and dots in mouth | Itching, wrists, ankles, genitals
50
Lichen planus | dx
Punch biopsy | Hep panel- can be sign of hep B or C and PBC
51
Lichen planus | trmt
Nonspecific | Most go away in 1 yr
52
Keratosis pilaris | cause
Hair follicles start to keratinized
53
Keratosis pilaris | PE
Hyperkeratotic “spiky” follicular papules on back of arms, thighs, face Red background Rough bumps that don't improve with scrubbing
54
Keratosis pilaris | trmt
Keratolytics | No scrubbing… be gentle
55
Acne vulgaris?
Disorder of pilosebaceous units of skin
56
Acne vulgaris | cause
Propionibacterium acnes | Multifactorial
57
Acne vulgaris | pe
Comedones on areas where there are lots of pilosebaceous units Open- black keratinous material Closed- skin colored dome shaped papules
58
Acne vulgaris | trmt
No gold standard Accutane is the only true cure bc it changes pilosebaceous glands- must be on 2 forms of birth control, TG each month, LFT each month, monthly office exam, dry skin is common SE, also nosebleeds
59
Perioral dermatitis | ?
Acne like inflammatory rash
60
Perioral dermatitis | causez
Unknown | Topical steroids, dental products, wind, stress
61
Perioral dermatitis | pe
1-2 mm red micropapules, microvesicles, micropustules with red background Around mouth, eyes, and nose
62
Perioral dermatitis | trmt
NO topical steroids… makes it worse (bc cause)
63
Acne Rosacea | ?
Chronic Inflammatory disorder that affects BV and pilosebaceous units on face Affects fitz 1 and 2 Looks like acne vulgaris but rosacea has no comedones
64
Trigger factors of Acne Rosacea
UV exposures, stress, hot drinks, alcohol, spicy foods, temps, wind
65
Acne Rosacea | pe
Redness followed by papules, pustules, and telangiectasia Papules and pustules on red background Best seen on central ⅓ of face
66
4 subtypes of Acne Rosacea
erythrotelangioctasis/ vascular- flushing and redness Papulopustular Phymatous- enlarged structure Ocular- watery/bloodshot eyes with tearing and burning
67
Otophyma
- big ear
68
Gnathophyma
- big mouth
69
Blepharophyma
- big eyelid
70
Acne Rosacea | trmt
Dec trigger factors Sunscreen Topical or systemic
71
Folliculitis?
Inflammation of hair follicle
72
Folliculitis cause
MC S aureus Pseudomonas aeruginosa in hot tub users Sweating and rubbing of tight clothes
73
Folliculitis pe
``` Asymptomatic Pustules around hair follicles Discrete individual lesions Not confluent but near each other Around butt, thigh, back ```
74
Folliculitis dx
Gram + cocci in gram stain if caused by s aureus
75
Folliculitis trmt
Hibiclens, bleach baths, clindamycin gel
76
Pseudofolliculitis barbae
hair renters skin and causes papules and pustules