skin 1.3 Flashcards

1
Q

Dermatofibrosarcoma protuberans pe

?

A

Slow growing tumor on shoulders or chest
Continued growth, irregular borders
Common in 20-50 yo

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2
Q

Dermatofibrosarcoma protuberans

dx

A

Punch or excisional biopsy

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3
Q

Dermatofibrosarcoma protuberans

trmt

A

Excision via MOHS surgery

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4
Q

Keloid?

A

Inc fibroblast activity

Common in darker skinned ppl

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5
Q

Keloid pe

A

Firm, plaque like papule or nodule that extends beyond trauma borders

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6
Q

Keloid trmt

A

1 is intralesional steroids: Kenalog 40

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7
Q

Dermatofibrosarcoma protuberans ?

A

Rare
Malignant dermal neoplasm
Don’t metastasize often

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8
Q

Lipoma ?

A

Benign tumor of subcutaneous fat

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9
Q

Lipoma sx

A

Asymptomatic

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10
Q

Lipoma pe

A

Skin colored
Elevation, Rubbery and movable
MC on trunk, neck, extremities

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11
Q

Lipoma dx

A

Biopsy if suspicious

Elliptical excision or punch biopsy to get all fat cells

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12
Q

Lipoma trmt

A

None

Cosmetic

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13
Q

Neurofibroma?

A

Proliferation of neural tissue in dermis

Benign

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14
Q

Neurofibroma pe

A

Skin colored papule or nodule

Buttonhole sign

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15
Q

Dx for NFM1- 2+ of following

A
6+ café au lait macules
2+ neurofibromas or 1 plexiform neurofibroma
Axillary or groin freckling
Optic nerve glioma
2+ lisch nodules (iris hamartomas)
Osseous lesions
1st degree relative with NFM 1
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16
Q

Neurofibroma trmt

A

Excision

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17
Q

xanthoma ?

A

Collection of lipids in dermis or tendons

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18
Q

Tendon xanthomas

A
  • stoney hard nodules on achilles tendon on extendor tendons of finger from high TC
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19
Q

Tuberous xanthomas-

A

potato like on butt and elbows from high TC or TG

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20
Q

Eruptive xanthomas-

A

on extensor surfaces from high TG

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21
Q

Xanthelasmas

A
  • on eyelids from high TC
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22
Q

Xanthoma trmt

A

Diet
Statins
Excision

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23
Q

Kaposi sarcoma

?

A

Malignant vasc tumor assoc with HHV8

Inc risk of malignant neurofibrosarcoma if involves mucous membranes

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24
Q

Kaposi sarcoma

types

A

Classic- old men eastern europe
Lymphadenopathic- young men in africa
AIDS associated

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25
Kaposi sarcoma | cause
AIDS, immunosuppression → must test for AIDS
26
Kaposi sarcoma | pe
Purple macules, papules, dermal plaques, nodules MC on legs in Classic KS Can be anywhere
27
Drug eruptions | ?
Systemic rash of sudden onset from drug
28
Drug eruptions | pe
hives Bright red macules or papules Start proximal then go distal
29
Drug eruptions | trmt
DC drug | May take 1-2 wks to clear
30
Viral exanthem
Virus spreads through the blood to the skin
31
Koplik spots-
tiny white papules with red base on buccal mucosa pathognomonic for measles
32
measles/rubeola
3 C’s: cough, coryza, conjunctivitis Begins on head then goes to extremities Can cause encephalitis
33
German measles/rubella
Begins on head then goes to extremities
34
Herpesvirus 6/roseola
Rose red macules | Fever goes away right before rash
35
Parvovirus B19/erythema infectiosum/ fifth disease
Slapped cheek then spreads to arms and legs and has reticular/lacy look
36
Enterovirus (echo and coxsackie virus from hand foot and mouth disease)
Vesicles on palms, soles, and mouth | Almost always have fever
37
Mono
Trmt with ampicillin or amoxicillin triples rash
38
Most have fever and constitutional sx before they appear
viral xanthems
39
SLE is mc in
MC women of childbearing age
40
SLE | sx
Fatigue, fever, arthralgia, weight change, alopecia, raynaud’s (white→ blue → red)
41
Dx american rheumatism association criteria- need 4+
``` Butterfly (malar) rash Discoid rash Photosensitivity Oral ulcers Arthritis Renal (worse prognosis), neuro, heme, or immunological disorders ANA ```
42
SLE | dx
ANA Anti ds DNA Anti sm a and b
43
SLE | trmt
Sunscreen Topical steroids Antimalarial hydroxychloroquine DOC
44
Cellulitis | cause
Staph, strep, H influenzae
45
Cellulitis | sx
Ill, febrile
46
Cellulitis | pe
``` 4 signs of inflammation: Rubor- red Calor- hot Tumor- swelling/edema Dolor- pain ```
47
Cellulitis | pe
Skin and blood culture
48
Cellulitis | trmt
Systemic ATB | Facial cellulitis needs IV trmt
49
Erysipelas
- sharp demarcated borders in strep infection
50
Abscess and furuncle | ?
Pus filled nodules in dermis | Furuncle- from infected hair follicle; abscess isnt
51
Abscess and furuncle | cause
S aureus is MC
52
Abscess and furuncle | sx
Painful, spongy red hard nodules Abscesses are larger and deeper No fever
53
Abscess and furuncle | dx
Culture
54
Abscess and furuncle | trmt
Incision and drain is gold std | Antiseptic skin cleansers and topical mupirocin
55
Hidradenitis suppurativa-
recurrent scarring and draining of nodules in axillae, groin, and under breasts
56
Erythema nodosum | ?
Inflammation of subcutaneous fat on lower legs
57
causes Erythema nodosum
Post strep, sarcoidosis, IBD, pregnancy
58
Erythema nodosum | pe
VERY tender red nodules 1-2 cm wide on lower legs | Self limiting, resolve in 3-6 wks
59
Erythema nodosum | dx
Throat culture if post strep Anti streptolysin O CXR if sarcoidosis Deep punch biopsy
60
Erythema nodosum | trmt
Treat cause | NSAIDS for pain
61
Fixed drug eruption | sx
Red plaques that come in the same spot every time you get exposed to a new med
62
Fixed drug eruption | causes
MC NSAIDS, sulfonamides, tetracyclines, one more got cut off
63
Urticaria/wheals | ?
Vascular red blanchable swelling skin that itches | Wheals last 30min-24 hrs
64
Urticaria/wheals | causes
Acute- resp infections and meds | Chronic- unknown
65
Urticaria/wheals | pe
Edematous plaques with pale centers and red borders
66
Urticaria/wheals | dx
LFT to r/o hepatitis | CBC to r/o heme causes
67
Urticaria/wheals | trmt
Stop meds | Antihistamine fexofenadine
68
MC event that comes before recurrent erythema multiforme
Herpes simplex infection is
69
Erythema multiforme | MCC
MCC meds and infections
70
Erythema multiforme | pe
Itch and burn Red papules and plaques Target lesions with 3 zones of color Usually on palms and soles
71
Erythema multiforme | dx
Tzanck prep or viral culture for vesicular lesions | Biopsy is diagnostic
72
Erythema multiforme | trmt
Stop meds | Treat herpes with valacyclovir
73
Steven johnson syndrome?
Erythema multiforme when mucous memb are involved
74
Drugs assoc with sjs:
sulfonamides, quinolones, cephalosporins, tetracyclines, phenobarbital, phenytoin, valproic acid, allopurinol
75
Steven johnson syndrome | pe
Vesicle and bullae | Up to 10% BSA
76
Steven johnson syndrome | trmt
Hospital Treat fluid loss Burn unit