cardio day 2 PP2 Flashcards
bnp
Secreted by cardiomyocytes when they stretch
Decreases resistance, increases natriuresis, increases EF
Indicates CHF, but can also go up with things such as exercise
CHF ?
Heart isn’t pumping enough to meet the body’s needs
Structural and functional changes
Impaired systolic and diastolic function
CHF patho
Excessive activation of SNS and RAAS causing LV remodeling
CHF sx
Exertional dyspnea, orthopnea, PND, edema, fatigue, weight gail, abd distension, chest congestion, cyanosis
Rales and edema do not always = HF
CHF dx
2D echo/doppler
Stages of CHF
CHF trmt
Drugs used to block SNS and RAAS: (know)
Beta blockers
ACEI and ARBs
Aldosterone antagonists
Systolic CHF
cause
HTN, valvular disease, CAD, myocarditis
Chemo, infiltrative process, hypothyroidism, arrhythmia
Systolic CHF sx
Resting SOB, dyspnea on exertion, fatigue, weight gain, weakness, sweating, orthopnea, PND, chest pain/angina
Systolic CHF pe
Rales, JVD, peripheral edema, ascites, S3 gallop, murmur (MR), lateral PMI, cool extremities, diminished peripheral impulses, hypotension
Systolic CHF dx
Echo- LV EF less than 40%, LA and LV enlargement, wall motion abnormalities
X ray- cardiomegaly, pulmonary edema, pleural effusions
ECG- Q waves, IVCD (intraventricular conduction delay), LBBB, Afib, ST/T changes
Labs- high BNP, hyponatremia, cardiac enzymes
Diastolic CHF?
Heart can’t fill well
HF with preserved EF
Usually in older women
Impaired ventricular filling, chamber stiffness, increased left ventricular end diastolic pressure (LVEDP), LVH with small LV cavity
risks Diastolic CHF
HTN, CKD, CAD, aortic stenosis, aortic insufficiency, obesity, restrictive CMP, atrial arrhythmias, mitral regurg
causes Diastolic CHF
Systolic dysfunction, HTN, aortic stenosis, aortic insufficiency, DM, tachycardia, AFib, ischemia, age, obesity, constrictive and restrictive CMP
sx Diastolic CHF (similar to CHF)
Resting SOB, dyspnea on exertion, fatigue, weakness, sweating, orthopnea, PND, chest pain/angina
Diastolic CHF pe
Rales, S4, aortic stenosis murmur, edema
Diastolic CHF dx
ECG- atrial arrhythmias, LVH, ischemic changes
X ray- pulmonary congestion
Labs- high bnp, cardiac enzymes, high Cr and BUN, proteinuria
Echo- diastolic dysfunction, LVH, aortic stenosis, restrictive physiology “stiff heart”