skeletal system Flashcards
functions of bones
- support
- protection
- helps with movement
- stores minerals
- stores energy
- produces blood cells
types of bones
- long bones: made of cortical (compact) bone
- short bones: as wide as long, mainly provide support
- flat bones: provide protection (skull)
- rregular bones: irregular shaped
epiphysis
long bone component
- end of long bone
- forms joints with other bones
- red bone marrow for hemtopoiesis (making RBCs)
diaphysis
long bone component
long, hollow shaft
medullary cavity
long bone component
within diaphysis, contains yellow and red marrow (fat storage)
metaphysis
long bone component
between epiphysis and diaphysis
epiphyseal plate
long bone component
- “growth plate”
- hyaline cartilage –> lengthens diaphysis in growth and ossification
cortical bone
- dense outer layer of bone
- supports weight of body
osteons
cortical bone component
functional unit
haversian canals
cortical bone component
“tubes” that contain blood vessels for nutrient supply
lamellae
cortical bone component
layers of osteon
lacunae
cortical bone component
spaces between lamellae and interconnect through canaliculi
canaliculi
cortical bone component
small channels that connect lacunae and haversian canals
volkmann’s canals
cortical bone component
connect Haversian canals to periosteum + provide nutrients
cancellous (spongy) bone
inner layer, soaks up red bon marrow via a web of trabeculae (CT that supports spongy bone)
bone remodeling
process of going back and forth between ossification (bone formation) and resorption (bone loss)
osteoprogenitors
immature precursor cells that differentiate into osteoblasts
osteoblasts
build bone around themselves, then mature into osteocytes once trapped in the bone matrix they created
* utilize Ca++ in blood to build bone
osteocytes
differentiaited osteoblasts, help exchange nutrients/waste with blood
* live in lacunae in osteons to maintain bone
osteoclasts
CRUSH or resorb bone, similar in structure to WBCs
* release Ca++ and phosphate into blood
* derived from monocytes
increase in Ca++ levels
calcitonin decreases osteoclast activity allowing osteoblasts to build bone
* this decreases Ca++ blood levels
decrease in Ca++ levels
- PTH stimulates osteoclasts relaeasing Ca++ therefore increase [Ca++] in blood
- vitamin D also increase Ca++ levels in blood by increasing intestinal Ca++ absorption
- PTH activates vitamin D
hydroxyapatite
mineral that forms bone containing Ca and PO4
* building/breaking down bone will decrease/increase blood Ca++ and HPO4- levels
* main component in enamel
intramembranous ossification
embryonic ossification
- mainly for flat bone (bones of skull except base and facial bones) and clavicle
- woven bone is formed directly without cartilage —> remodeled later to lamellar bone
endochondral ossification
embryonic ossification
- mainly for long bones (axial and appendicular skeletal) + base of skull
- cartilage models made by chondrocytes –> calcifies during fetal development and creates ossification centers
- osteoclasts and blasts replace it with woven bone –> then later lamellar bone
types of connective tissue
- loose
- adipose
- blood
- fibrous
- bone