skeletal system Flashcards

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1
Q

functions of bones

A
  1. support
  2. protection
  3. helps with movement
  4. stores minerals
  5. stores energy
  6. produces blood cells
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2
Q

types of bones

A
  • long bones: made of cortical (compact) bone
  • short bones: as wide as long, mainly provide support
  • flat bones: provide protection (skull)
  • rregular bones: irregular shaped
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3
Q

epiphysis

long bone component

A
  • end of long bone
  • forms joints with other bones
  • red bone marrow for hemtopoiesis (making RBCs)
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4
Q

diaphysis

long bone component

A

long, hollow shaft

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5
Q

medullary cavity

long bone component

A

within diaphysis, contains yellow and red marrow (fat storage)

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6
Q

metaphysis

long bone component

A

between epiphysis and diaphysis

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7
Q

epiphyseal plate

long bone component

A
  • “growth plate”
  • hyaline cartilage –> lengthens diaphysis in growth and ossification
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8
Q

cortical bone

A
  • dense outer layer of bone
  • supports weight of body
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9
Q

osteons

cortical bone component

A

functional unit

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10
Q

haversian canals

cortical bone component

A

“tubes” that contain blood vessels for nutrient supply

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11
Q

lamellae

cortical bone component

A

layers of osteon

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12
Q

lacunae

cortical bone component

A

spaces between lamellae and interconnect through canaliculi

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13
Q

canaliculi

cortical bone component

A

small channels that connect lacunae and haversian canals

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14
Q

volkmann’s canals

cortical bone component

A

connect Haversian canals to periosteum + provide nutrients

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15
Q

cancellous (spongy) bone

A

inner layer, soaks up red bon marrow via a web of trabeculae (CT that supports spongy bone)

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16
Q

bone remodeling

A

process of going back and forth between ossification (bone formation) and resorption (bone loss)

17
Q

osteoprogenitors

A

immature precursor cells that differentiate into osteoblasts

18
Q

osteoblasts

A

build bone around themselves, then mature into osteocytes once trapped in the bone matrix they created
* utilize Ca++ in blood to build bone

19
Q

osteocytes

A

differentiaited osteoblasts, help exchange nutrients/waste with blood
* live in lacunae in osteons to maintain bone

20
Q

osteoclasts

A

CRUSH or resorb bone, similar in structure to WBCs
* release Ca++ and phosphate into blood
* derived from monocytes

21
Q

increase in Ca++ levels

A

calcitonin decreases osteoclast activity allowing osteoblasts to build bone
* this decreases Ca++ blood levels

22
Q

decrease in Ca++ levels

A
  • PTH stimulates osteoclasts relaeasing Ca++ therefore increase [Ca++] in blood
  • vitamin D also increase Ca++ levels in blood by increasing intestinal Ca++ absorption
  • PTH activates vitamin D
23
Q

hydroxyapatite

A

mineral that forms bone containing Ca and PO4
* building/breaking down bone will decrease/increase blood Ca++ and HPO4- levels
* main component in enamel

24
Q

intramembranous ossification

embryonic ossification

A
  • mainly for flat bone (bones of skull except base and facial bones) and clavicle
  • woven bone is formed directly without cartilage —> remodeled later to lamellar bone
25
Q

endochondral ossification

embryonic ossification

A
  • mainly for long bones (axial and appendicular skeletal) + base of skull
  • cartilage models made by chondrocytes –> calcifies during fetal development and creates ossification centers
  • osteoclasts and blasts replace it with woven bone –> then later lamellar bone
26
Q

types of connective tissue

A
  • loose
  • adipose
  • blood
  • fibrous
  • bone