Skeletal Muscle Relaxants

Question 1

Metabolite of atracurium that lowers the seizure threshold

Answer 1

Laudanosine

Question 2

Neuromuscular blocker that undergoes elimination in bile

Answer 2

Vecuronium

Question 3

Sugammadex is a novel reversal agent specific for which neuromuscular blocker?

Answer 3

Rocuronium

Question 4

Drug used to treat strychnine poisoning

Answer 4

Pancuronium

Question 5

Three components of lethal injection

Answer 5

Thiopental 5 g
Pancuronium 100 mg
Potassium chloride 100 mEq

Question 6

The only depolarizing neuromuscular blocker

Answer 6

Succinylcholine

Question 7

Antidote for malignant hyperthermia

Answer 7

Dantrolene

Question 8

Among nondepolarizing neuromuscular blockers, this drug has the most rapid onset time of 60-120 seconds.

Answer 8

Rocuronium

Question 9

In this skeletal muscle relaxant, muscle relaxation is potentiated by inhaled anesthetics, aminglycosides, and quinidine.

Answer 9

Vecuronium

Question 10

Sudden release of calcium in the sarcoplasmic reticulum is a side effect of succinylcholine when given with this inhaled anesthetic.

Answer 10

Halothane

Question 11

Dantrolene blocks what channel in the skeletal muscle?

Answer 11

RyR1 Ca2+ release channel

Question 12

This centrally acting spasmolytic agent is used to treat severe spasticity secondary to cerebral palsy.

Answer 12

Baclofen