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Pharmacology > Antiarrhythmic Drugs > Flashcards

Antiarrhythmic Drugs Flashcards

1
Q

Local anesthetic that is the drug of choice for venticular arrhythmias post-myocardial infarction

A

Lidocaine

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2
Q

Drug of choice for torsades de pointes

A

Magnesium sulfate

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3
Q

Class IA antiarrhythmics’ effect on the action potential duration

A

Prolong AP

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4
Q

Class IB antiarrhythmics’ effect on the action potential duration

A

Shorten AP

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5
Q

Class IC antiarrhythmics’ effect on the action potential duration

A

No effect

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6
Q

Most selective subclass of class I antiarrhythmics

A

Class IB

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7
Q

Three class IA antiarrhythmics

A

Disopyramide
Procainamide
Quinidine

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8
Q

Class IA overdose is treated with:

A

Sodium lactate

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9
Q

Class IA antiarrhythmic that can induce lupus

A

Procainamide

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10
Q

Quinidine, an antimalarial, is under what class of antiarrhythmics?

A

IA

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11
Q

This class IA antiarrhythmic has a long duration of action and produces marked antimuscarinic effects

A

Disopyramide

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12
Q

Four class IB antiarrhythmics

A

Lidocaine
Mexiletine
Phenytoin
Tocainide

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13
Q

Agranulocytosis is a serious side effect of this class IB antiarrhythmic

A

Tocainide

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14
Q

Class IC antiarrhythmics are reserved for refractory arrhythmias due to their high arrhythmogenicity. What is their effect on the ECG?

A

Increase QRS duration

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15
Q

Four class IC antiarrhythmics

A

Encainide
Flecainide
Moricizine
Propafenone

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16
Q

Drugs (2) used for Wolff-Parkinson-White

A

Amiodarone

Procainamide

17
Q

Class 2 antiarrhythmics act on this phase of the action potential

A

Phase 4

18
Q

Class 1 antiarrhythmics act on this phase of the action potential

A

Phase 0

19
Q

Class 3 antiarrhythmics act on this phase of the action potential

A

Phase 3

20
Q

Drug of choice for thyrotoxic arrhythmias

A

Propranolol

21
Q

Class 2 antiarrhythmics are also known as this drug class

A

Beta blockers

22
Q

Class 2 anitiarrhythmic that has class 3 properties

A

Sotalol

23
Q

Class 3 antiarrhythmic effect on AP duration

A

Prolonged AP duration

24
Q

Channel blocked by class 3 antiarrhythmics

A

IK potassium channels

25
Q

Most efficacious of all antiarrhythmics

A

Amiodarone

26
Q

What is the effect of amiodarone on thyroid function when used for more than 2 weeks? What is this phenomenon called?

A

Hyperthyroid

Jod-Basedow phenomenon

27
Q

Indications for dofetilide and ibutilide

A

Treatment and prophylaxis of atrial fibrillation

28
Q

Effect of class 4 antiarrhythmic on the ECG

A

Prolonged PR interval

29
Q

Drug of choice for paroxysmal supraventricular tachycardia

A

Adenosine

Pharmacology (22 decks)

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