Antiarrhythmic Drugs

Question 1

Local anesthetic that is the drug of choice for venticular arrhythmias post-myocardial infarction

Answer 1

Lidocaine

Question 2

Drug of choice for torsades de pointes

Answer 2

Magnesium sulfate

Question 3

Class IA antiarrhythmics’ effect on the action potential duration

Answer 3

Prolong AP

Question 4

Class IB antiarrhythmics’ effect on the action potential duration

Answer 4

Shorten AP

Question 5

Class IC antiarrhythmics’ effect on the action potential duration

Answer 5

No effect

Question 6

Most selective subclass of class I antiarrhythmics

Answer 6

Class IB

Question 7

Three class IA antiarrhythmics

Answer 7

Disopyramide
Procainamide
Quinidine

Question 8

Class IA overdose is treated with:

Answer 8

Sodium lactate

Question 9

Class IA antiarrhythmic that can induce lupus

Answer 9

Procainamide

Question 10

Quinidine, an antimalarial, is under what class of antiarrhythmics?

Answer 10

IA

Question 11

This class IA antiarrhythmic has a long duration of action and produces marked antimuscarinic effects

Answer 11

Disopyramide

Question 12

Four class IB antiarrhythmics

Answer 12

Lidocaine
Mexiletine
Phenytoin
Tocainide

Question 13

Agranulocytosis is a serious side effect of this class IB antiarrhythmic

Answer 13

Tocainide

Question 14

Class IC antiarrhythmics are reserved for refractory arrhythmias due to their high arrhythmogenicity. What is their effect on the ECG?

Answer 14

Increase QRS duration

Question 15

Four class IC antiarrhythmics

Answer 15

Encainide
Flecainide
Moricizine
Propafenone

Question 16

Drugs (2) used for Wolff-Parkinson-White

Answer 16

Amiodarone

Procainamide

Question 17

Class 2 antiarrhythmics act on this phase of the action potential

Answer 17

Phase 4

Question 18

Class 1 antiarrhythmics act on this phase of the action potential

Answer 18

Phase 0

Question 19

Class 3 antiarrhythmics act on this phase of the action potential

Answer 19

Phase 3

Question 20

Drug of choice for thyrotoxic arrhythmias

Answer 20

Propranolol

Question 21

Class 2 antiarrhythmics are also known as this drug class

Answer 21

Beta blockers

Question 22

Class 2 anitiarrhythmic that has class 3 properties

Answer 22

Sotalol

Question 23

Class 3 antiarrhythmic effect on AP duration

Answer 23

Prolonged AP duration

Question 24

Channel blocked by class 3 antiarrhythmics

Answer 24

IK potassium channels

Question 25

Most efficacious of all antiarrhythmics

Answer 25

Amiodarone

Question 26

What is the effect of amiodarone on thyroid function when used for more than 2 weeks? What is this phenomenon called?

Answer 26

Hyperthyroid | Jod-Basedow phenomenon

Question 27

Indications for dofetilide and ibutilide

Answer 27

Treatment and prophylaxis of atrial fibrillation

Question 28

Effect of class 4 antiarrhythmic on the ECG

Answer 28

Prolonged PR interval

Question 29

Drug of choice for paroxysmal supraventricular tachycardia

Answer 29

Adenosine