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Pharmacology > Local Anesthetics > Flashcards

Local Anesthetics Flashcards

1
Q

Local anesthetic with the longest half-life

A

Ropivacaine

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2
Q

What is the half-life of procaine?

A

1-2 mins (shortest among local anesthetics)

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3
Q

All local anesthetics are vasodilators except?

A

Cocaine

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4
Q

Local anesthetic that causes methemoglobinemia

A

Prilocaine

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5
Q

What is the effect of hypercalcemia and hyperkalemia on local anesthetic activity?

A

Hypercalcemia: antagonizes local anesthetic activity
Hyperkalemia: enhances local anesthetic activity

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6
Q

Local anesthetics block what channel to prevent depolarization and action potential propagation along axons?

A

Voltage-dependent Na+ channels

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7
Q

Enumerate the four amide local anesthetics

A

Bupivacaine
Lidocaine
Prilocaine
Ropivacaine

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8
Q

Bupivacaine and ropivacaine cardiotoxicity is treated with?

A

Intralipid

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Pharmacology (22 decks)

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