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Side effects Flashcards

1
Q

Which drugs prolong the QT interval?

A

Some Risky Meds Can Prolong QT

  • Sotalol (class III except Amiodarone)
  • Risperidone/Ziprasidone
  • Macrolides
  • Chloroquine
  • Protease inhibitors
  • Quinidine (all class IA)
  • TCAs and Thiazides
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2
Q

Which drugs can cause seizures?

A

I BITE My tongue

  • Isoniazid (B6 deficiency)
  • Buproprion
  • Imipenem/cilastatin
  • Tramadol
  • Enflurane
  • Metoclopramide
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3
Q

Which drugs can cause diarrhea?

A

Might Excite Colon On Accident

  • Metformin
  • Erythromycin
  • Colchicine
  • Orlistat
  • Acarbose
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4
Q

Which drugs can cause thrombocytopenia?

A
  • Heparin (HIT - antibody against Heparin-PF4 complex activates platelets)
  • Cimetidine
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5
Q

Which drugs can cause focal to massive hepatic necrosis?

A

Liver HAVAc

  • Halothane
  • Amanitoxin
  • Valproate
  • Acetaminophen
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6
Q

What can cause Fanconi Syndrome?

A

Expired tetracyclines, heavy metals (?)

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7
Q

What drugs can cause Cinchonism?

A

Quinine and Quinidine

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8
Q

Which drugs can cause megaloblastic anemia?

A

PMS is a BLAST

  • Phenytoin
  • Methotrexate
  • Sulfa drugs
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9
Q

Which drugs can cause hot flashes?

A

Tamoxifen and clomiphene

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10
Q

What drugs can cause acute cholestatic hepatitis and jaundice?

A

Erythromycin

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11
Q

What drugs can cause Parkinsonianism?

A

Parkinsonism is cogwheel rigidity of the ARM:

  • Antipsychotics (high potency esp)
  • Reserpine
  • Metoclopramide
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12
Q

What drugs can cause tardive dyskinesia?

A
  • High potency antipsychotics
  • Metoclopramide
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13
Q

Which are the sulfa drugs?

A

Popular FACTSSS-D

  • Probenecid
  • Furosemide
  • Acetazolamide
  • Celecoxib
  • Thiazides
  • Sulfasalazine
  • Sulfamethoxazole/Sulfadiazine
  • Sulfonylureas (glyburide)
  • Dapsone
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14
Q

Which drugs can cause SIADH?

A

Can’t Concentrate Serum Sodium

  • Carbamazepine
  • Cyclophosphamide
    • SSRIs
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15
Q

Which drugs can cause hypothyroidism?

A
  • Lithium
  • Amiodarone
  • Sulfonamides
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16
Q

Which drugs can cause Methemoglobinemia?

A

a Methemoglobinemic Patient is Not Always Something Deadly

  • Metoclopramide
  • Procaine
  • Nitrates
  • Antimalarials
  • Sulfonamides
    • Dapsone
17
Q

Which drugs can cause hepatitis?

A

Isoniazid

18
Q

Which drugs can cause gingival hyperplasia?

A

PVC

  • Phenytoin
  • Verapamil & Nifedipine
  • Cyclosporine
19
Q

Hyperuricemia

A

Painful Tophi and Feet Need Care

  • Pyrazinamide
  • Thiazides
  • Furosemide
  • Niacin
  • Cyclosprine
20
Q

Steven-Johnson syndrome

A
  • Penicillin
  • Allopurinol
  • Sulfa drugs (Popular FACTSSS-D)
  • Antiepileptics
    • Carbamazepine
    • Lamotrigine
    • Phenytoin
    • Phenobarbital
    • Ethosuximide
21
Q

Diabetes Insipidus

A

Lithium and demeclocycline

22
Q

Pulmonary Fibrosis

A
  • Bleomycin
  • Busulfan
  • Amiodarone
  • Methotrexate
23
Q

Agranulocytosis

A

Drugs CCCrush Myeloblasts and Promyeloblasts

  • Dapsone
  • Carbamazepine
  • Colchicine
  • Clozapine
  • Methimazole
  • Propylthiouracil
24
Q

Aplastic Anemia

A

Can’t Make New Blood Cells Properly

  • Carbamazepine
  • Methimazole
  • NSAIDs
  • Benzene
  • Chloramphenicol
  • Propylthiouracil
25
Q

Hemorrhagic cystitis

A

Cyclophosphamide and ifofosfamide

Prevent with Mesna

26
Q

Interstitial Nephritis

A

Fuck My Nephrons

  • Furosemide
  • Methicillin
  • NSAIDs
27
Q

Fat redistribution

A

Glucocorticoids and Protease Inhibitors

28
Q

Photosensitivity

A

i SAT For a photo

  • Sulfa drugs
  • Amiodarone
  • Tetracyclines
  • 5-FU
29
Q

Myopathy

A

FuCkinG Hydro NIPS

  • Fibrates
  • Colchicine
  • Glucocorticoids
  • Hydrochloroquine
  • Niacin
  • IFN-alpha
  • Penicillamine
  • Statins
30
Q

Cutaneous Flushing

A

VANC

  • Vancomycin
  • Adenosine
  • Niacin
  • Ca++ channel blockers
31
Q

Direct Coombs+ Hemolytic Anemia

A

Methyldopa and Penicillin

32
Q

Hyperglycemia

A

Taking Pills Necessitates Having Blood Checked

  • Tacrolimus
  • Protease Inhibitors
  • Niacin
  • HCTZ
  • Beta-blockers
  • Corticosteroids
33
Q

Hemolysis in G6PD

A

Hemolysis IS D PAIN

  • Isoniazid
  • Sulfa drugs
  • Dapsone
  • Penicillin
  • Aspirin
  • Ibuprofen
  • Nitrofurantoin
34
Q

Pancreatitis

A

Drugs Causing A Violent Abdominal Distress

  • Didanosine
  • Corticosteroids
  • Acute Alcohol
  • Valproate
  • Azathioprine
  • Diuretics: furosemide & HCTZ
35
Q

What does ticlopidine do? What is its side effect?

A

ADP-receptor blocker like clopidogrel. Neutropenia, which presents with mouth ulcers and fever.

36
Q

Ganciclovir and Zidovudine

A

Ganciclovir: neutropenia, anemia, thrombocytopenia, renal

Zidovudine: bone marrow suppression

37
Q

Which drugs cause drug-induced lupus?

A

SHIPP

  • sulfa drugs
  • hydralazine
  • isoniazid
  • procainamide
  • phenytoin

all STEP 1 (34 decks)

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