resp facts

Question 1

Criteria for ARDS? Pathophys? Radiology?

Contrast with pathophys for emphysema.

Answer 1

• Alveolar endothelial damage - capillary leakage (exudative phase)
  
  • vs emphysema: alveolar wall damage
• maybe fibroproliferative stage; then fibrosis (honeycombing) or resolution
• PaO2 / FIO2 < 200
• Normal LA pressure (PWCP)
• Fluffy white opacification on plain film

Question 2

Mechanism of asthma airway obstruction?

Answer 2

• Pulmonary inflammation caused by leukotrienes
• Hyperresponsiveness to e.g. exercise or cold climate.