Sedation & Analgesia - QUIZ Flashcards

1
Q

NSAIDs mechanism of action is related to:

A

Inhibition of COX

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2
Q

Which NSAID has variable effects when given IV?

A

Ketorolac

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3
Q

Cox-2 specific NSAIDs have reduced risk of GI bleeding.

True or False?

A

True

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4
Q

Name the major opioid antagonist:

A

Naloxone

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5
Q

What is NOT a common physical effect of narcotic drugs?

A

Cough

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6
Q

Which opioid has the best oral bio-availability?

A

Methadone

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7
Q

What is true regarding Fentanyl’s pharmacokinetics?

A

Increased duration of action when tissues are saturated

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8
Q

What is true regarding the mechanism of action of benzodiazepines?

A

Binds to GABA receptors to produce inhibitory actions

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9
Q

What is true regarding barbiturates and benzodiazepines actions on GABA:

A

Benzodiazepines increase frequency of Chloride channel opening

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10
Q

What are dose dependent effects of benzodiazepines and barbiturates?

A

Anticonvulsant
Medullary depression
Anesthesia
Anxiolysis

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11
Q

Name the stages of anesthesia in order:

A
  1. Analgesia
  2. Disinhibition
  3. Surgical anesthesia
  4. Medullary depression
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12
Q

The mechanisms of action of general anesthetics are varied, but they generally decrease the threshold for firing of CNS neurons.

True or False?

A

False

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13
Q

Which general anesthetic does not work on GABAA receptors?

A

Ketamine

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14
Q

Analgesics are defined as drugs that relieve pain, and are classified as:

A

Adjuvants
Co-analgesics
Opioid
Non-Opioid

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