Diabetes Melitus - QUIZ

Question 1

All of the following about Insulin administration are true, except:

a) Insulin lowers plasma glucose levels by enhancing glucose transport into the cell
b) Insulin inhibits Lipolysis
c) The most significant safety concern surrounding insulin use is incorrect dosing leading to hyperglycemia
d) It is important to understand the different formulations of insulin, to appreciate their onset and duration of action

Answer 1

c) The most significant safety concern surrounding insulin use is incorrect dosing leading to hyperglycemia

Question 2

Rapid acting insulin such as lispro:

a) Have an onset of action of approximately 10 minutes and last up to 1 hour
b) Have an onset of action of approximately 30 minutes and last up to 5 hours
c) Have an onset of action which is immediate and last up to 5 hours
d) Have an onset of action of approximately 10 minutes and last up to 5 hours

Answer 2

b) Have an onset of action of approximately 30 minutes and last up to 5 hours

Question 3

Since insulin is a polypeptide it is susceptible to degradation in the intestinal tract and thus must be given via SC, or IV.

True or False?

Answer 3

True

Question 4

Due to Metformin’s action on the liver, patients receiving metformin are at increased risk of:

a) Increased Bilirubin
b) Increased Lactate
c) Increased Urea
d) Increased ALT/AST

Answer 4

b) Increased Lactate

Question 5

Match the following Classification of oral Anti-hyperglycemic medication with the corresponding Mechanism of Action.

a) SGLT2 Inhibitors
b) Biguanides
c) Sulphonylureas
i) Enhances Glucagon-like peptide-1, & reduces glucagon action, reducing gluconeogenesis & gl
ii) Stimulate the pancreas to secrete more insulin by blocking ATP-sensitive K+ channels
iii) Increased glucosuria through the inhibition of SGLT-2 in the kidney

Answer 5

a) SGLT2 Inhibitors = iii)
b) Biguanides = i)
c) Sulphonylureas = ii)

Question 6

An insulin pump is a small microcomputer that:
Select ALL that apply.
a) Contains long acting insulin that is administered through an SQ catheter
b) Contains rapid acting insulin that is administered through an SQ catheter
c) Is programmed to bolus insulin timed with meals
d) Is programmed to give small amounts of insulin continuously

Answer 6

b) Contains rapid acting insulin that is administered through an SQ catheter
d) Is programmed to give small amounts of insulin continuously

Question 7

An Insulin pump mimics the body’s natural insulin response and results in improved glucose control but does have increased risk of DKA.

True or False?

Answer 7

True