Antidepressants/Antipsychotics - QUIZ Flashcards
Please name the MOA of the following antidepressants:
a) Serotonin modulators
b) Noradrenergic & specific serotonergic antidepressants
c) Serotonin-norepinephrine reuptake inhibitors (SNRIs)
d) Monomaine oxidase inhibitors (MAOIs)
e) Tricyclic antidepressants (TCAs)
f) Selective serotonin reuptake inhibitors (SSRIs)
a) Serotonin modulators selectively inhibit serotonin & act as 5HT2 antagonist
b) Noradrenergic & specific serotonergic antidepressants block presynaptic alpha 2 receptors
c) Serotonin-norepinephrine reuptake inhibitors (SNRIs) inhibit reuptake of serotonin and norepi, weakly inhibit dopamine reuptake
d) Monomaine oxidase inhibitors (MAOIs) competitively inhibit MAO
e) Tricyclic antidepressants (TCAs) inhibit reuptake of norepi & serotonin into presynaptic terminals
f) Selective serotonin reuptake inhibitors (SSRIs) selectively inhibit serotonin reuptake at presynaptic membrane
Despite most antidepressant medications taking 1-2 weeks to start showing mood-elevating effects, the synaptic effects of these agents occur within hours. True or False?
True
Follow up from previous question: The time course of the adverse effects of these agents follow the mood elevating effects. True or False?
False
All Antipsychotic medications exert their effects through which of the following mechanism?
a) Increase Serotonergic neurotransmission
b) Increase Dopaminergic neurotransmission
c) Reduce Dopaminergic neurotransmission
d) Reduce Serotonergic neurotransmission
c) Reduce Dopaminergic neurotransmission
Haloperidol can proarrhythmic effects include which of the following:
a) AV conduction blocks
b) QTc prolongation
c) QRS widening
d) AVNRT
b) QTc prolongation
When comparing various agents for use in agitated/combative patients, which of the following is more rapidly acting with a better safety profile:
a) Olanzapine
b) Citalopram
c) Midazolam
d) Haloperidol
c) Midazolam
