Adrenergic Agonists - QUIZ Flashcards

1
Q

Alpha and Beta agonists mimic the actions of the parasympathetic nervous system. True or False?

A

False

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2
Q

List the effects of the following adrenergic receptors: A1, A2, B1, B2

A

A1: Vasoconstriction of arteries & veins, slight coronary artery constriction
A2: Constricts coronary arterioles, decreases insulin secretion, inhibits lipolysis
B1: Increased SA node firing rate & ventricular contraction, vasodilates renal arteries
B2: Vasodilation, decreased PVR, muscle and liver glycogenolysis

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3
Q

List the 5 ways indirect adrenergic agonists exert their effects:

A
Releasing endogenous hormones
Uptake inhibition
MAO inhibition
COMT inhibition
Releasing agents
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4
Q

Adrenergic agonists are classified by 3 components. Name them.

A

Receptor site
Whether they act directly or indirectly
Whether they have dual effects

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5
Q

Beta-adrenoceptors normally bind to which of the following:

a) Norepinephrine released by sympathetic adrenergic nerves
b) Circulating Norepinephrine
c) Epinephrine released by sympathetic adrenergic nerves
d) Circulating Epinephrine

A

a) & d)

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6
Q

Beta adrenergic agonist’s positive inotropic effects are mediated by:

A

Increased cAMP

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7
Q

Activation of which of the adrenoreceptors causes bronchodilation?

A

Beta 2

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8
Q

Alpha adrenergic agonist bind to alpha receptors and cause:

A

Vasoconstriction of both arteries and veins, but more pronounced in the arterioles

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9
Q

Which of the following is a result of strict alpha agonism?

a) Reflex tachycardia
b) Reflex Bradycardia
c) Portal HTN
d) Decreased CVP

A

b)

Note: vasoconstriction can increase BP, therefore trigger baroreceptors resulting in reflex bradycardia

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