Adrenergic Agonists - QUIZ Flashcards
Alpha and Beta agonists mimic the actions of the parasympathetic nervous system. True or False?
False
List the effects of the following adrenergic receptors: A1, A2, B1, B2
A1: Vasoconstriction of arteries & veins, slight coronary artery constriction
A2: Constricts coronary arterioles, decreases insulin secretion, inhibits lipolysis
B1: Increased SA node firing rate & ventricular contraction, vasodilates renal arteries
B2: Vasodilation, decreased PVR, muscle and liver glycogenolysis
List the 5 ways indirect adrenergic agonists exert their effects:
Releasing endogenous hormones Uptake inhibition MAO inhibition COMT inhibition Releasing agents
Adrenergic agonists are classified by 3 components. Name them.
Receptor site
Whether they act directly or indirectly
Whether they have dual effects
Beta-adrenoceptors normally bind to which of the following:
a) Norepinephrine released by sympathetic adrenergic nerves
b) Circulating Norepinephrine
c) Epinephrine released by sympathetic adrenergic nerves
d) Circulating Epinephrine
a) & d)
Beta adrenergic agonist’s positive inotropic effects are mediated by:
Increased cAMP
Activation of which of the adrenoreceptors causes bronchodilation?
Beta 2
Alpha adrenergic agonist bind to alpha receptors and cause:
Vasoconstriction of both arteries and veins, but more pronounced in the arterioles
Which of the following is a result of strict alpha agonism?
a) Reflex tachycardia
b) Reflex Bradycardia
c) Portal HTN
d) Decreased CVP
b)
Note: vasoconstriction can increase BP, therefore trigger baroreceptors resulting in reflex bradycardia