Antibiotics - QUIZ Flashcards

1
Q

Which of the following factors drive microbial resistance?

a) Incorrect use of broad-spectrum agents
b) Non- compliance
c) All of the options
d) Excess antibiotic usage
e) Incorrect dosing

A

c) All of the options

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2
Q

The pharmacokinetic activity of antibiotics can be described by which of the following?

a) Antibiotics kill according to time spent over MIC and concentration
b) Antibiotics kill according to concentration
c) Antibiotics kill according to time spent over MIC
d) All of the options

A

d) All of the options

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3
Q

Which of the following antibiotics demonstrate “time-dependent killing”

a) Fluroquinolones
b) Aminoglycosides
c) Beta Lactams
d) Tetracyclines

A

c) Beta Lactams

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4
Q

Which of the following is true regarding the toxic effects of aminoglycosides?

a) None of the options
b) Aminoglycosides toxicity is closely related to hepatic function
c) Aminoglycosides can cause permanent nephrotoxicity
d) Aminoglycosides’ toxicity is closely related to duration of therapy

A

c) Aminoglycosides can cause permanent nephrotoxicity

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5
Q

Please pair the following classification of antibiotics with their mechanism of action:

a) Cephalosporin ii) Disrupts bacterial cell wall
b) Aminoglycosides iii) Disrupts bacterial DNA or RNA Synthesis
c) Fluoroquinolones i) Inhibit protein synthesis

A

a) Cephalosporin disrupts bacterial cell walls (ii)
b) Aminoglycosides inhibit protein synthesis (i)
c) Fluoroquinolones disrupt bacterial DNA or RNA Synthesis (iii)

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6
Q

Which of the following class of antibiotics potentiates the nephrotoxicity of aminoglycosides?

a) Carbapenems
b) Cephalosporins
c) Macrolides
d) Fluoroquinolones

A

b) Cephalosporins

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7
Q
Which of the following agents can exacerbate myasthenia gravis? 
Select all that apply.
a) Aminoglycosides 
b) All of the options
c) Cephalosporines 
d) Macrolides
A

a) Aminoglycosides

d) Macrolides

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