Direct Acting Vasodilators - QUIZ Flashcards
Which of the following describes the effects of Hydralazine?
a) Dilates resistance arteries and veins
b) Decreases venous sympathetic tone
c) Dilates resistance arterioles, with no effect on venoconstriction
d) Directly dilates vascular smooth muscle
c) Dilates resistance arterioles, with no effect on venoconstriction
Why is hydralazine often combined with a sympathetic inhibitor?
a) None of the options
b) Baroreflex-mediated venoconstriction and catecholamine mediated inotrope and chronotrope combat its effects
c) cAMP mediated increase in inotrope and chronotrope
d) Hydralazine directly agonizes beta adrenergic receptors
b) Baroreflex-mediated venoconstriction and catecholamine mediated inotrope and chronotrope combat its effects
Nitroprusside is metabolized it forms which of the following toxic metabolites? Select all that apply. a) Cyanide b) Glucuronic acid c) Thiocyanate d) Formic acid
a) Cyanide
c) Thiocyanate
Which of the following is true regarding adverse effects of Hydralazine?
a) It can cause a lupus syndrome
b) It can cause sodium wasting
c) It can cause increased ICP
d) It can cause bradycardic arrhythmias
a) It can cause a lupus syndrome* (it can also increase ICP, sent to Sean for review)
Which of the following is true regarding the vascular systems response to Nitrates?
a) There is a graded response throughout the vascular system
b) Nitrates strictly effect the venous system
c) Nitrates strictly effect arterioles
d) All vasculature is affected to the same degree
a) There is a graded response throughout the vascular system
Which of the following is true regarding the system effects of Nitric oxide release from nitroglycerine and nitroprusside:
a) Decreased platelet aggregation
b) Increased renal sodium and water wasting
c) Increased pulmonary vascular resistance
d) Decreased venous capacity with increased ventricular afterload
a) Decreased platelet aggregation
